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Mouse Anti-TRIM66 Recombinant Antibody (CBYJT-4827) (CBMAB-T4370-YJ)

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Summary

Host Animal
Mouse
Specificity
Human, Rat, Mouse
Clone
CBYJT-4827
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Specific for an epitope mapping between amino acids 1006-1026 within an internal region of TRIM66 of human origin
Specificity
Human, Rat, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1006-1026

Target

Full Name
Tripartite Motif Containing 66
Introduction
TRIM66 (Tripartite Motif Containing 66) is a Protein Coding gene. Gene Ontology (GO) annotations related to TRIM66 include protein homodimerization activity and chromatin binding. An important paralog of TRIM66 is TRIM24.
Entrez Gene ID
Human9866
Mouse330627
Rat361623
UniProt ID
HumanO15016
MouseQ924W6
RatF1M6Z0
Alternative Names
Tripartite Motif Containing 66; C11orf29; Transcriptional Intermediary Factor 1 Delta; Tripartite Motif-Containing Protein 66; Chromosome 11 Open Reading Frame 29; Tripartite Motif-Containing 66; TIF1DELTA; KIAA0298; TIF1D
Function
May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association (By similarity).
Biological Process
Nucleus
Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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