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Recombinant Mouse Anti-TriMethyl-HIST3H3-K27 Antibody (CBAb252) (CBMAB-Ab252-LY)

The product is antibody recognizes TriMethyl-HIST3H3-K27. The antibody immunoassay techniques such as: WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200; IP 1:50-1:200; ChIP 1:20-1:100.
Host Animal
Mouse
Application
WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200; IP 1:50-1:200; ChIP 1:20-1:100
Immunogen
A synthetic methylated peptide corresponding to residues surrounding K27 of human histone H3
Antibody Isotype
IgG
Specificity
Human
Cross Reactivity
Human, Mouse, Rat
Clone
CBAb252
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Alternative Name
HIST3H3; H3.4; H3/g; H3FT; H3t; histone H3.1t
Entrez Gene ID
UniProt ID
Cat CBMAB-Ab252-LY
Conjugates
Size
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