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Mouse Anti-TSC22D1 Monoclonal Antibody (V2-879) (CBMAB-0274-LY)

This product is mouse monoclonal antibody recognizes TSC22D1 of human. The antibody 1A2 immunoassay techniques such as: IP, MA, WB.
See all TSC22D1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-879
Antibody Isotype
IgG1
Application
IP, MA, WB

Basic Information

Immunogen
Recombinant peptide (Protein Domain)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TSC22D1
Introduction
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Entrez Gene ID
8848
UniProt ID
Q15714
Alternative Names
TGFB1I4; TSC22
Function
Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.
Biological Process
Biological Process negative regulation of apoptotic process Source:GO_Central1 Publication
Biological Process positive regulation of cell population proliferation Source:GO_Central1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:InterPro
Biological Process transcription by RNA polymerase II Source:ProtInc1 Publication
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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