Mouse Anti-TTC4 Recombinant Antibody (CBYJT-5139) (CBMAB-T4717-YJ)

Name: Mouse Anti-TTC4 Recombinant Antibody (CBYJT-5139)
SKU: CBMAB-T4717-YJ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBYJT-5139

Application

ELISA, WB

Immunogen

Partial recombinant corresponding to aa1-100 from human TTC4 (NP_004614) with GST tag. MW of the GST tag alone is 26kD

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.2

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-100

More Infomation

Target

Full Name

tetratricopeptide repeat domain 4

Introduction

TTC4 is a protein that contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity. TTC4 interacts with heat shock proteins 70 and 90.

Entrez Gene ID

7268

UniProt ID

O95801

Alternative Names

Tetratricopeptide Repeat Domain 4; TPR Repeat Protein 4; Tetratricopeptide Repeat Protein 4; CNS1

Function

May act as a co-chaperone for HSP90AB1 (PubMed:18320024).
Promotes Sendai virus (SeV)-induced host cell innate immune responses (PubMed:29251827).

Biological Process

Biological Process defense response to virus Source:UniProtKB1 Publication
Biological Process innate immune response Source:UniProtKB1 Publication
Biological Process protein folding Source:GO_Central1 Publication

Cellular Location

Nucleus
Nucleus, nucleoplasm
Cytoplasm
Predominantly nuclear in the G1 and S phases of cell cycle and is evenly distributed between the nucleus and cytoplasm in the G2 phase (By similarity).
MSL1 can promote its nuclear localization (By similarity).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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