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Mouse Anti-TUBG2 Recombinant Antibody (CBYJT-5366) (CBMAB-T4966-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TUBG2 (Tubulin Gamma 2). The antibody can be used for immunoassay techniques, such as ELISA, IF, WB.
See all TUBG2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-5366
Antibody Isotype
IgG2a, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa1-101 from human TUBG2 (NP_057521) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-101

Target

Full Name
tubulin, gamma 2
Introduction
TUBG2 (Tubulin Gamma 2) is a Protein Coding gene. Among its related pathways are PAK Pathway and PI3K-Akt signaling pathway. Gene Ontology (GO) annotations related to TUBG2 include GTP binding and structural molecule activity. An important paralog of TUBG2 is TUBG1.
Entrez Gene ID
UniProt ID
Alternative Names
Tubulin Gamma 2; Gamma-2-Tubulin; Tubulin Gamma 2 Chain; Tubulin Gamma-2 Chain; Tubulin, Gamma 2
Function
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
Biological Process
Biological Process cytoplasmic microtubule organization Source:InterPro
Biological Process meiotic spindle organization Source:GO_Central1 Publication
Biological Process microtubule cytoskeleton organization Source:GO_Central1 Publication
Biological Process microtubule nucleation Source:GO_Central1 Publication
Biological Process mitotic cell cycle Source:GO_Central1 Publication
Biological Process mitotic sister chromatid segregation Source:GO_Central1 Publication
Biological Process mitotic spindle organization Source:GO_Central1 Publication
Cellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
PTM
Phosphorylation at Ser-131 by BRSK1 regulates centrosome duplication, possibly by mediating relocation of gamma-tubulin and its associated proteins from the cytoplasm to the centrosome.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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