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Mouse Anti-UBE2R2 Recombinant Antibody (CBWJC-4575) (CBMAB-C5978WJ)

This product is a Mouse antibody that recognizes UBE2R2. This antibody CBWJC-4575 can be used for immunoassay techniques such as: WB, IP, IF, IHC, ELISA.
See all UBE2R2 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBWJC-4575
Antibody Isotype
IgG
Application
WB, IP, IF, IHC, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ubiquitin-conjugating enzyme E2R 2
Introduction
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human54926
Mouse67615
Rat689226
UniProt ID
HumanQ712K3
MouseQ6ZWZ2
RatB2RZ96
Alternative Names
Ubiquitin Conjugating Enzyme E2 R2; Ubiquitin-Conjugating Enzyme E2-CDC34B; E2 Ubiquitin-Conjugating Enzyme R2; Ubiquitin Carrier Protein R2; Ubiquitin-Protein Ligase R2; CDC34B; UBC3B; Ubiquitin-Conjugating Enzyme E2R 2;
Function
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin.
Biological Process
Biological Process protein K48-linked ubiquitination Source:UniProtKB1 Publication
Biological Process protein monoubiquitination Source:UniProtKB1 Publication
Biological Process protein polyubiquitination Source:GO_Central1 Publication
Biological Process ubiquitin-dependent protein catabolic process Source:GO_Central1 Publication
Cellular Location
Cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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