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Mouse Anti-UBXN10 Recombinant Antibody (2F6) (CBMAB-C4413-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2F6
Antibody Isotype
IgG1
Application
FC, IF, WB

Basic Information

Immunogen
Full length human recombinant protein of human UBXN10 (NP_689589) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% Sodium azide

Target

Full Name
UBX domain protein 10
Introduction
VCP/p97-binding protein required for ciliogenesis (PubMed:26389662). Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B (IFT-B) in cilia (PubMed:26389662). UBX domain-containing proteins act as tethering factors for VCP/p97 and may specify substrate specificity of VCP/p97 (PubMed:26389662).
Entrez Gene ID
127733
UniProt ID
Q96LJ8
Alternative Names
UBX Domain Protein 10; UBX Domain-Containing Protein 3; UBX Domain Containing 3; UBXD3; UBX Domain-Containing Protein 10;
Function
VCP/p97-binding protein required for ciliogenesis (PubMed:26389662).
Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B (IFT-B) in cilia (PubMed:26389662).
UBX domain-containing proteins act as tethering factors for VCP/p97 and may specify substrate specificity of VCP/p97 (PubMed:26389662).
Biological Process
Biological Process cilium assembly Source:UniProtKB1 Publication
Biological Process ubiquitin-dependent ERAD pathway Source:GO_Central1 Publication
Cellular Location
Cell projection, cilium
Recruited to cilia in a VCP-dependent manner.
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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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