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Mouse Anti-UBXN11 Recombinant Antibody (1B10) (CBMAB-C4414-CN)

This product is a Mouse antibody that recognizes UBXN11. The antibody 1B10 can be used for immunoassay techniques such as: ELISA, IF, WB.
See all UBXN11 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B10
Application
ELISA, IF, WB

Basic Information

Immunogen
UBXN11 (NP_663320.1, aa 311-409) partial recombinant protein with GST tag
Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4

Target

Full Name
UBX domain protein 11
Introduction
This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Entrez Gene ID
91544
UniProt ID
Q5T124
Alternative Names
UBX Domain Protein 11; Socius; Colorectal Tumor-Associated Antigen COA-1; UBX Domain-Containing Protein 5; UBXD5; SOC; Colorectal Tumor-Associated Antigen-1;
Function
May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 and RND3. Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity).
Biological Process
Biological Process proteasome-mediated ubiquitin-dependent protein catabolic process Source:GO_Central1 Publication
Cellular Location
Cytoplasm, cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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