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Mouse Anti-UGGT2 Recombinant Antibody (CBFYH-2829) (CBMAB-H3898-FY)

This product is mouse antibody that recognizes UGGT2. The antibody CBFYH-2829 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all UGGT2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-2829
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
UDP-glucose glycoprotein glucosyltransferase 2
Introduction
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.
Entrez Gene ID
55757
UniProt ID
Q9NYU1
Alternative Names
UDP-Glucose Glycoprotein Glucosyltransferase 2; UDP-Glucose Ceramide Glucosyltransferase-Like 1; UDP-Glucose Ceramide Glucosyltransferase-Like 2; UDP-Glucose:Glycoprotein Glucosyltransferase 2; UGCGL2; HUGT2
Function
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Biological Process
Biological Process endoplasmic reticulum mannose trimming Source:Reactome
Biological Process ER-associated misfolded protein catabolic process Source:GO_Central1 Publication
Biological Process protein N-linked glycosylation via asparagine Source:GO_Central1 Publication
Cellular Location
Endoplasmic reticulum lumen
Endoplasmic reticulum-Golgi intermediate compartment
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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