Sign in or Register   Sign in or Register
  |  

Mouse Anti-ULK4 Recombinant Antibody (4A10-1A7) (CBMAB-C4630-CN)

This product is a Mouse antibody that recognizes ULK4. The antibody 4A10-1A7 can be used for immunoassay techniques such as: ELISA, WB.
See all ULK4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4A10-1A7
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa 1-581 from human ULK4 (AAH14794) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
unc-51-like kinase 4 (C. elegans)
Introduction
This gene encodes a member of the unc-51-like serine/threonine kinase (STK) family. Members of this protein family play a role in neuronal growth and endocytosis. The encoded protein is likely involved in neurite branching, neurite elongation and neuronal migration. Genome-wide association studies (GWAS) indicate an association of variations in this gene with blood pressure and hypertension. Sequence variations in this gene may also be be associated with psychiatric disorders, including schizophrenia and bipolar disorder. Pseudogenes associated with this gene have been identified and are located on chromosome 15. [provided by RefSeq, Jul 2016]
Entrez Gene ID
54986
UniProt ID
Q96C45
Alternative Names
Unc-51 Like Kinase 4; Serine/Threonine-Protein Kinase ULK4; Unc-51-Like Kinase 4 (C. Elegans); Unc-51-Like Kinase 4; EC 2.7.11.1; REC01035; FAM7C1;
Function
May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.
Biological Process
Biological Process microtubule cytoskeleton organization Source:MGI1 Publication
Biological Process protein phosphorylation Source:InterPro
Biological Process regulation of JNK cascade Source:MGI1 Publication
Biological Process regulation of MAPK cascade Source:MGI1 Publication
Biological Process regulation of neuron migration Source:MGI1 Publication
Biological Process regulation of neuron projection development Source:MGI1 Publication
Biological Process regulation of p38MAPK cascade Source:MGI1 Publication
Biological Process regulation of protein kinase C signaling Source:MGI1 Publication
Involvement in disease
Various anomalies in ULK4 gene have been reported for several cases of schizophrenia, schizophrenia plus bipolar disorder and autism. ULK4 gene has been proposed to be a rare susceptibility risk factor for a range of psychiatric diseases including schizophrenia.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-ULK4 Recombinant Antibody (4A10-1A7)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare