Mouse Anti-UNKL Recombinant Antibody (F-8) (CBMAB-C4689-CN)

Name: Mouse Anti-UNKL Recombinant Antibody (F-8)
SKU: CBMAB-C4689-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

F-8

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 586-680 mapping at the C-terminus of UNKL of human origin

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

Unkempt Family Like Zinc Finger

Introduction

This gene encodes a RING finger protein that may function in Rac signaling. It can bind to Brg/Brm-associated factor 60b and can promote its ubiquitination. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Entrez Gene ID

64718

UniProt ID

Q9H9P5

Alternative Names

Unkempt Family Like Zinc Finger; Zinc Finger CCCH Domain-Containing Protein 5-Like; RING Finger Protein Unkempt-Like; Unkempt Family Zinc Finger-Like; C16orf28; ZC3HDC5L; ZC3H5L;

Function

May participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven.

Biological Process

Biological Process protein ubiquitination Source:UniProtKB-UniPathway

Cellular Location

Isoform 4
Cytoplasm
Nucleus
Isoform 4 is primarily localized in the cytoplasm but has the ability to shuttle between the nucleus and the cytoplasm.

PTM

Isoform 4 is ubiquitinated in the C-terminal. Ubiquitination is enhanced by activated RAC1. The presence of the RING finger domain is not essential for ubiquitination to occur.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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