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Mouse Anti-UQCR10 Recombinant Antibody (2B5) (CBMAB-C4724-CN)

This product is a Mouse antibody that recognizes UQCR10. The antibody 2B5 can be used for immunoassay techniques such as: ELISA.
See all UQCR10 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2B5
Antibody Isotype
IgG2b, κ
Application
ELISA

Basic Information

Immunogen
Full length recombinant corresponding to aa 1-64 from UCRC (AAH05402) with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
Ubiquinol-Cytochrome C Reductase, Complex III Subunit X
Introduction
UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995 [PubMed 8592474]).[supplied by OMIM, Mar 2008]
Entrez Gene ID
29796
UniProt ID
Q9UDW1
Alternative Names
Ubiquinol-Cytochrome C Reductase, Complex III Subunit X; Ubiquinol-Cytochrome C Reductase, Complex III Subunit X, 7.2kDa; Ubiquinol-Cytochrome C Reductase Complex 7.2 KDa Protein; Cytochrome C1 Non-Heme 7 KDa Protein; Complex III Subunit 9; UCRC; Ubiquinol-Cytochrome C Reductase Complex (7.2 KD); Cytochrome C1, Nonheme 7kDa Protein;
Function
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
Biological Process
Biological Process cellular respiration Source:ComplexPortal1 Publication
Biological Process mitochondrial electron transport, ubiquinol to cytochrome c Source:GO_Central1 Publication
Cellular Location
Mitochondrion inner membrane
Topology
Mitochondrial matrix: 2-21
Helical: 22-47
Mitochondrial intermembrane: 48-63
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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