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Mouse Anti-USP13 Monoclonal Antibody (2H7) (CBMAB-0292-LY)

This product is mouse monoclonal antibody recognizes USP13 of human. The antibody 2H7 immunoassay techniques such as: IP, ELISA.
Host Species
Mouse
Application
IP, ELISA
Immunogen
Recombinant peptide (Full Length)
Antibody Isotype
IgG1
Specificity
Human
Clone
2H7
Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum-associated degradation (ERAD). Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. In turn, PIK3C3/VPS34-containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13.
Alternative Name
IsoT-3
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0292-LY
Conjugates
Size
Price $
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Second antibody and isotype control