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Mouse Anti-USPL1 (aa 975-1074) Recombinant Antibody (2F12) (CBMAB-U0056-CQ)

This product is a mouse antibody that recognizes USPL1 (aa 975-1074). The antibody 2F12 can be used for immunoassay techniques such as: WB, IP, ELISA.
See all USPL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2F12
Antibody Isotype
IgG
Application
WB, IP, ELISA

Basic Information

Immunogen
Partial recombinant corresponding to amino acids 975-1074 from USPL1 (NP_005791)
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95% as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 975-1074

Target

Full Name
ubiquitin specific peptidase like 1
Introduction
USPL1 (Ubiquitin Specific Peptidase Like 1) is a component of complexes that can bind to U snRNA genes.
Entrez Gene ID
10208
UniProt ID
Q5W0Q7
Alternative Names
USPL1; ubiquitin specific peptidase like 1; C13orf22, chromosome 13 open reading frame 22; ubiquitin-specific peptidase-like protein 1; bA121O19.1; D13S106E; highly charged protein; C13orf22; FLJ32952; RP11-121O19.1; DKFZp781K2286
Function
SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for SUMO2 and SUMO3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms (PubMed:22878415).
Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (PubMed:24413172).
Is a component of complexes that can bind to U snRNA genes (PubMed:24413172).
Biological Process
Biological Process Cajal body organization Source:UniProtKB1 Publication
Biological Process cell population proliferation Source:UniProtKB1 Publication
Biological Process protein desumoylation Source:UniProtKB1 Publication
Biological Process snRNA transcription Source:UniProtKB1 Publication
Cellular Location
Nucleus, Cajal body
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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