Mouse Anti-USPL1 (aa 975-1074) Recombinant Antibody (2F12) (CBMAB-U0056-CQ)

Name: Mouse Anti-USPL1 (aa 975-1074) Recombinant Antibody (2F12)
SKU: CBMAB-U0056-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

2F12

Application

WB, IP, ELISA

Immunogen

Partial recombinant corresponding to amino acids 975-1074 from USPL1 (NP_005791)

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

>95% as determined by SDS-PAGE analysis

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 975-1074

More Infomation

Target

Full Name

ubiquitin specific peptidase like 1

Introduction

USPL1 (Ubiquitin Specific Peptidase Like 1) is a component of complexes that can bind to U snRNA genes.

Entrez Gene ID

10208

UniProt ID

Q5W0Q7

Alternative Names

USPL1; ubiquitin specific peptidase like 1; C13orf22, chromosome 13 open reading frame 22; ubiquitin-specific peptidase-like protein 1; bA121O19.1; D13S106E; highly charged protein; C13orf22; FLJ32952; RP11-121O19.1; DKFZp781K2286

Function

SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for SUMO2 and SUMO3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms (PubMed:22878415).
Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (PubMed:24413172).
Is a component of complexes that can bind to U snRNA genes (PubMed:24413172).

Biological Process

Biological Process Cajal body organization Source:UniProtKB1 Publication
Biological Process cell population proliferation Source:UniProtKB1 Publication
Biological Process protein desumoylation Source:UniProtKB1 Publication
Biological Process snRNA transcription Source:UniProtKB1 Publication

Cellular Location

Nucleus, Cajal body

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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