Mouse Anti-UTP3 Recombinant Antibody (CBXU-169) (CBMAB-U0112-CQ)

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Basic Information

Host Animal
Mouse
Clone
CBXU-169
Application
WB
Immunogen
Partial sequence of recombinant full-length protein to human UTP3
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 1% BSA
Preservative
0.05% sodium azide
Concentration
0.1 mg/mL
Purity
>95% as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
UTP3, Small Subunit Processome Component
Introduction
Mpp10's factor network by identifying two new binding partners, the biogenesis factor Utp3/Sas10 and the ribosomal protein Rps5/uS7 and mapped the respective regions within Mpp10 required for these interactions.
Entrez Gene ID
UniProt ID
Alternative Names
CRL1; CRLZ1; SAS10
Orthologs
mouse all
Function
Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity).
Biological Process
Biological Process brain development Source:UniProtKB
Biological Process chromatin organization Source:UniProtKB-KW
Biological Process maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source:GO_Central1 Publication
Cellular Location
Nucleus
PTM
Citrullinated by PADI4.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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