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Rabbit Anti-VASN Recombinant Antibody (CBYY-1266) (CBMAB-1274-YY)

This product is rabbit antibody that recognizes VASN. The antibody CBYY-1266 can be used for immunoassay techniques such as: ELISA(Cap)
See all VASN antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBYY-1266
Antibody Isotype
IgG
Application
ELISA(Cap)

Basic Information

Immunogen
Recombinant Human Vasorin Protein (Catalog#13854-H08H)
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Vasorin
Introduction
This gene encodes a WD repeat-containing protein that functions to preserve and regulate the activity of the USP12-UAF1 deubiquitinating enzyme complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]
Entrez Gene ID
114990
UniProt ID
Q6EMK4
Alternative Names
WD Repeat Domain 20; WD Repeat-Containing Protein 20; Protein DMR; DMR;
Function
May act as an inhibitor of TGF-beta signaling.
Biological Process
Biological Process cellular response to hypoxia Source:Ensembl
Biological Process cellular response to redox state Source:Ensembl
Biological Process negative regulation of epithelial to mesenchymal transition Source:UniProtKB1 Publication
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway Source:UniProtKB1 Publication
Cellular Location
Membrane
Secreted
Topology
Extracellular: 24-575
Helical: 576-596
Cytoplasmic: 597-673
PTM
N-glycosylated. N-glycan heterogeneity at Asn-117: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), Hex6HexNAc5 (minor) and dHex1Hex6HexNAc5 (minor).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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