Human Recombinant VASN protein, His Tag (V2LY-0526-LY6870)

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Basic Information

Expressed Host
HEK293 Cells
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant VASN protein, His Tag consist of Amino Acid: 1-575 and predicts a molecular mass of 61.1 kDa.
Molecule Mass
61.1 kDa
Sequence
Amino Acid: 1-575
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
Vasorin
Function
May act as an inhibitor of TGF-beta signaling.
Biological Process
Biological Process cellular response to hypoxia Source:Ensembl
Biological Process cellular response to redox state Source:Ensembl
Biological Process negative regulation of epithelial to mesenchymal transition Source:UniProtKB1 Publication
Biological Process negative regulation of transforming growth factor beta receptor signaling pathway Source:UniProtKB1 Publication
Cellular Location
Membrane
Secreted
Topology
Extracellular: 24-575
Helical: 576-596
Cytoplasmic: 597-673
PTM
N-glycosylated. N-glycan heterogeneity at Asn-117: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), Hex6HexNAc5 (minor) and dHex1Hex6HexNAc5 (minor).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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