Mouse Anti-VAX1 Recombinant Antibody (CBYY-1309) (CBMAB-1329-YY)

Name: Mouse Anti-VAX1 Recombinant Antibody (CBYY-1309)
SKU: CBMAB-1329-YY
Rating: 5 (1 reviews)

See all VAX1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-1309

Application

ELISA, WB

Immunogen

Partial recombinant corresponding to aa1-101 from human VAX1 (NP_954582) with GST tag. MW of the GST tag alone is 26kD

Specificity

Human, Mouse, Rabbit

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

ventral anterior homeobox 1

Introduction

This gene encodes a homeo-domain containing protein from a class of homeoBovinex transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of Bovinedy development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeoBovinex gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforMouse have been found for this gene.

Entrez Gene ID

Human	11023
Mouse	22326
Rabbit	100351281

UniProt ID

Human	Q5SQQ9
Mouse	Q2NKI2
Rabbit	G1T5K8

Alternative Names

Ventral Anterior HomeoBovinex 1; MCOPS11;

Function

Transcription factor that may function in dorsoventral specification of the forebrain. Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk (By similarity).

Biological Process

Biological Process astrocyte differentiation Source:Ensembl
Biological Process axon guidance Source:Ensembl
Biological Process brain development Source:Ensembl
Biological Process camera-type eye development Source:Ensembl
Biological Process central nervous system development Source:GO_Central1 Publication
Biological Process negative regulation of neuroblast proliferation Source:Ensembl
Biological Process neuroblast proliferation Source:Ensembl
Biological Process neuroepithelial cell differentiation Source:Ensembl
Biological Process neuron differentiation Source:GO_Central1 Publication
Biological Process neuron migration Source:Ensembl
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process roof of mouth development Source:Ensembl
Biological Process skeletal muscle cell differentiation Source:Ensembl

Cellular Location

Nucleus

Involvement in disease

Microphthalmia, syndromic, 11 (MCOPS11):
A rare clinical entity including as main characteristics microphthalmia and small optic nerves, cleft lip and palate, absence of corpus callosum, hippocampal malformations, and absence of the pineal gland. Microphthalmia is a disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-VAX1 Recombinant Antibody (CBYY-1309)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-VAX1 Recombinant Antibody (CBYY-1561) (CAT#: CBMAB-1631-YY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry