Mouse Anti-WDR36 Recombinant Antibody (1D6) (CBMAB-W0037-WJ)

Name: Mouse Anti-WDR36 Recombinant Antibody (1D6)
SKU: CBMAB-W0037-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1D6

Application

ELISA, WB

Immunogen

WDR36 (NP_644810, aa853-951) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: SGIETELRSL SPDCGGSIEV MQSFLKMIGM MLDRKRDFEL AQAYLALFLK LHLKMLPSEP VLLEEITNLS SQVEENWTHL QSLFNQSMCI LNYLKSALL

Specificity

Human

Antibody Isotype

IgG2a, к

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

WD repeat domain 36

Introduction

WDR36 is a protein-coding gene encodes a member of the WD repeat protein family. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Diseases associated with WDR36 include Glaucoma 1, Open Angle, G and Open-Angle Glaucoma. The related pathways are Gene Expression and rRNA processing in the nucleus and cytosol.

Entrez Gene ID

134430

UniProt ID

Q8NI36

Alternative Names

GLC1G; UTP21; TAWDRP; TA-WDRP

Function

Involved in the nucleolar processing of SSU 18S rRNA. Involved in T-cell activation and highly coregulated with IL2.

Biological Process

Biological Process response to stimulus Source:UniProtKB-KW
Biological Process rRNA processing Source:GO_Central1 Publication
Biological Process visual perception Source:UniProtKB-KW

Cellular Location

Nucleus, nucleolus

Involvement in disease

Glaucoma 1, open angle, G (GLC1G):
A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. However, glaucoma can occur at any intraocular pressure. The disease is generally asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-WDR36 Recombinant Antibody (CBWJW-001) (CAT#: CBMAB-W0160-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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