Mouse Anti-WDR6 Recombinant Antibody (2D4) (CBMAB-W0070-WJ)

Name: Mouse Anti-WDR6 Recombinant Antibody (2D4)
SKU: CBMAB-W0070-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2D4

Application

ELISA, WB

Immunogen

WDR6 (AAH02826, aa1-289) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2a, λ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

WD repeat domain 6

Introduction

WDR6 is a protein-coding gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes.

Entrez Gene ID

11180

UniProt ID

Q9NNW5

Alternative Names

WDR6; WD repeat domain 6

Function

Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.

Biological Process

Biological Process G1 to G0 transition Source:UniProtKB1 Publication
Biological Process negative regulation of autophagy Source:BHF-UCL1 Publication
Biological Process negative regulation of cell population proliferation Source:UniProtKB1 Publication
Biological Process tRNA methylation Source:GO_Central1 Publication

Cellular Location

Cytoplasm
Colocalizes in the cytoplasm with STK11/LKB1.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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