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Mouse Anti-WDR6 Recombinant Antibody (2D4) (CBMAB-W0070-WJ)

This product is a mouse antibody that recognizes WDR6. The antibody 2D4 can be used for immunoassay techniques such as: ELISA, WB.
See all WDR6 antibodies
Published Data
Fig.1 Semi-quantitative RT-PCR analysis of gene expressions in different regions of rat brain.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
2D4
Antibody Isotype
IgG2a, λ
Application
ELISA, WB

Basic Information

Immunogen
WDR6 (AAH02826, aa1-289) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, λ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
WD repeat domain 6
Introduction
WDR6 is a protein-coding gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes.
Entrez Gene ID
11180
UniProt ID
Q9NNW5
Alternative Names
WDR6; WD repeat domain 6
Function
Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.
Biological Process
Biological Process G1 to G0 transition Source:UniProtKB1 Publication
Biological Process negative regulation of autophagy Source:BHF-UCL1 Publication
Biological Process negative regulation of cell population proliferation Source:UniProtKB1 Publication
Biological Process tRNA methylation Source:GO_Central1 Publication
Cellular Location
Cytoplasm
Colocalizes in the cytoplasm with STK11/LKB1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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