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Mouse Anti-WHSC1 Monoclonal Antibody (2A11) (CBMAB-0304-LY)

This product is mouse monoclonal antibody recognizes WHSC1 of human. The antibody 2A11 immunoassay techniques such as: IP, MA.
Host Species
Mouse
Application
IP, MA
Immunogen
Recombinant peptide (Protein Domain)
Antibody Isotype
IgG2a
Specificity
Human
Clone
2A11
Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Histone methyltransferase with histone H3 'Lys-27' (H3K27me) methyltransferase activity. Isoform 2 may act as a transcription regulator that binds DNA and suppresses IL5 transcription through HDAC recruitment.
Alternative Name
MMSET; NSD2
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0304-LY
Conjugates
Size
Price $
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Second antibody and isotype control