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Mouse Anti-YARS1 Recombinant Antibody (CBYJT-5591) (CBMAB-T5224-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to YARS (Tyrosyl-TRNA Synthetase). The antibody can be used for immunoassay techniques, such as WB, IP, ICC, Dot.
See all YARS1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat, Mouse
Clone
CBYJT-5591
Antibody Isotype
IgG1
Application
WB, IP, ICC, Dot

Basic Information

Immunogen
Recombinant fragment corresponding to Human Tyrosyl tRNA synthetase/ TyrRS.
Specificity
Human, Rat, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Introduction
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Cytokine activities have also been found for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
Entrez Gene ID
Human8565
Mouse107271
Rat313047
UniProt ID
HumanP54577
MouseQ91WQ3
RatQ4KM49
Alternative Names
Tyrosyl-TRNA Synthetase; Tyrosine TRNA Ligase 1, Cytoplasmic; EC 6.1.1.1; TYRRS; Tyrosyl-TRNA Synthetase, Cytoplasmic; Tyrosine--TRNA Ligase, Cytoplasmic
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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