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Mouse Anti-ZFAT Recombinant Antibody (CBWJZ-067) (CBMAB-Z0196-WJ)

This product is a mouse antibody that recognizes ZFAT. The antibody CBWJZ-067 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all ZFAT antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBWJZ-067
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
ZFAT
Introduction
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated.
Entrez Gene ID
Human57623
Mouse380993
Rat362925
UniProt ID
HumanQ9P243
MouseQ7TS63
RatD4A2U0
Alternative Names
ZFAT1; ZNF406
Function
May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).
Biological Process
Biological Process hematopoietic progenitor cell differentiation Source:Ensembl
Biological Process regulation of DNA-templated transcription Source:GO_Central1 Publication
Biological Process spongiotrophoblast layer development Source:Ensembl
Cellular Location
Nucleus
Cytoplasm, cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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