Rat Anti-ZFP42 Recombinant Antibody (CBWJZ-075) (CBMAB-Z0228-WJ)

Name: Rat Anti-ZFP42 Recombinant Antibody (CBWJZ-075)
SKU: CBMAB-Z0228-WJ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Rat

Clone

CBWJZ-075

Application

ELISA, ICC, WB

Immunogen

E. coli-derived recombinant human Rex-1 (AA1-150).

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Solid

Concentration

0.5 mg/mL

More Infomation

Target

Full Name

ZFP42 Zinc Finger Protein

Introduction

ZFP42 (ZFP42 Zinc Finger Protein) is a Protein Coding gene. Diseases associated with ZFP42 include Mixed Germ Cell Cancer. Among its related pathways are Cardiac Progenitor Differentiation and Preimplantation Embryo. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is YY1.

Entrez Gene ID

132625

UniProt ID

Q96MM3

Alternative Names

ZFP42 Zinc Finger Protein; Reduced Expression Protein 1; Zinc Finger Protein 754; Zfp-42; ZNF754; REX-1; REX1

Function

Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal (By similarity).

Biological Process

Biological Process female gonad development Source:UniProtKB1 Publication
Biological Process male gonad development Source:UniProtKB1 Publication
Biological Process meiotic cell cycle Source:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication

Cellular Location

Nucleus

PTM

Polyubiquitinated by RNF12, leading to proteasomal degradation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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