Mouse Anti-ZHX3 Monoclonal Antibody (1G3) (CBMAB-0391-LY)

Name: Mouse Anti-ZHX3 Monoclonal Antibody (1G3)
SKU: CBMAB-0391-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1G3

Application

IP, MA, WB

Immunogen

Recombinant peptide (Full Length)

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

ZHX3

Introduction

This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA.

Entrez Gene ID

23051

UniProt ID

Q9H4I2

Alternative Names

KIAA0395; TIX1

Function

Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA.

Biological Process

Biological Process cell differentiation Source:UniProtKB-KW
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process positive regulation of osteoblast differentiation Source:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-ZHX3 Monoclonal Antibody (1D11) (CAT#: CBMAB-0390-LY)

Mouse Anti-ZHX3 Recombinant Antibody (1D9) (CAT#: CBMAB-Z0258-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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