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Mouse Anti-ZNF131 Recombinant Antibody (CBWJZ-160) (CBMAB-Z0334-WJ)

This product is a mouse antibody that recognizes ZNF131. The antibody CBWJZ-160 can be used for immunoassay techniques such as: WB.
See all ZNF131 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJZ-160
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Synthetic peptide corresponding to the N-terminal region of human ZNF131.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
zinc finger protein 131
Introduction
ZNF131 (Zinc Finger Protein 131) is a Protein Coding gene. Diseases associated with ZNF131 include Split-Hand/Foot Malformation 1 and Joubert Syndrome 1. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZBTB17.
Entrez Gene ID
7690
UniProt ID
P52739
Alternative Names
ZBTB35; pHZ-10
Function
Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity).
May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling.
Biological Process
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
Sumoylation does not affect nuclear localization.
PTM
Monosumoylated at Lys-601 by CBX4 and UHRF2. Sumoylation may potentiate ZNF131 inhibition of estrogen signaling. Sumoylation does not interfere with ubiquitination.
Ubiquitinated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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