Mouse Anti-ZNF488 Recombinant Antibody (1B6) (CBMAB-0808-LY)

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Basic Information

Host Animal
Mouse
Clone
1B6
Application
IP, MA
Immunogen
Recombinant peptide (aa 170-307)
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
ZNF488
Introduction
ZNF488 may be involved in transcriptional regulation.
Entrez Gene ID
UniProt ID
Alternative Names
FLJ32104
Function
Transcriptional repressor. Plays a role in oligodendrocyte differentiation, together with OLIG2. Mediates Notch signaling-activated formation of oligodendrocyte precursors. Promotes differentiation of adult neural stem progenitor cells (NSPCs) into mature oligodendrocytes and contributes to remyelination following nerve injury.
Biological Process
Biological Process negative regulation of DNA-templated transcription Source:Ensembl
Biological Process oligodendrocyte development Source:GO_Central1 Publication
Biological Process positive regulation of myelination Source:Ensembl
Biological Process positive regulation of oligodendrocyte differentiation Source:Ensembl
Biological Process regulation of DNA-templated transcription Source:GO_Central1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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