Anti-CDH1 Antibody (CBMAB-C4370-CQ) Immunohistochemistry Kit (V2LY-0826-LY187)

Name: Anti-CDH1 Antibody (CBMAB-C4370-CQ) Immunohistochemistry Kit
SKU: V2LY-0826-LY187
Rating: 5 (1 reviews)

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Summary

Product Overview

This comprehensive, all-in-one kit is designed for the precise immunohistochemical (IHC) detection of target protein in tissue samples. Unlike standard detection kits, it includes a highly specific rabbit primary antibody bundled directly with our robust Polymer HRP detection system. The kit provides every essential reagent needed for the entire IHC workflow-from the initial antigen retrieval buffer to the final mounting media. By offering a pre-matched primary antibody with optimized buffers and secondary detection reagents, this kit eliminates the need for tedious protocol optimization and reagent sourcing, ensuring consistent, high-quality staining results.

Primary Antibody Cat.

CBMAB-C4370-CQ

Primary Antibody

Mouse Anti-ERG Recombinant Antibody (CBFYE-1186)

Secondary Antibody Host Species

Goat

Secondary Antibody Species Specificity

Rabbit

Application

IHC-P

Sample Type

FFPE tissue

Test Size

50 Tests

Storage

Stored at 2-8°C. The kit is stable for 6 months from the date of receipt.

Key Features

Target-Specific Primary Antibody

Includes a highly validated rabbit primary antibody, ensuring reliable and specific target localization.

Complete End-to-End Solution

Contains all 11 essential components required for a full IHC workflow, including Tris-EDTA Antigen Retrieval Buffer, Blocking Buffer, Polymer HRP-Goat anti-Rabbit Secondary Antibody, DAB Chromogens, Counterstain, and Mounting Media.

Streamlined Workflow

Pre-optimized reagents work seamlessly with the included primary antibody, saving researchers significant time on antibody titration and protocol adjustments.

Sample Compatibility

Highly recommended and optimized for Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.

Kit Capacity

Provides sufficient reagents (50T) to perform 50 tests, depending on tissue section size.

More Infomation

Sub Cat	Reagents	Size
LV01	Antigen Retrieval Buffer (50× Tris-EDTA)	100 ml
LV02	Washing Buffer (30×)	120 ml
LV03	Blocking Buffer	5 ml
LV04	Quenching buffer (RTU)	5 ml
LV05	Primary Antibody Diluent (RTU)	100 ml
LV06R	HRP-Goat anti-Rabbit Secondary Antibody	5 ml
LV07	Chromogen Component A	0.2 ml
LV08	Chromogen Component B	4 ml
LV09	Signal Enhancer	5 ml
LV10	Counter Staining Reagent	5 ml
LV11	Mounting Media	5 ml

Dang, D. N. T., Nguyen, H. T. T., Ngo, H. D., Tran, B. M., Vu, A. D., & Dang, H. Q. (2021). A novel stop codon mutation in exon 5 (c. 639G> A) of the cadherin-1 gene in a Vietnamese man with hereditary diffuse gastric cancer: a case report. Journal of Medical Case Reports, 15(1), 1-5.

Yang, C. C., Wei, X. P., Fu, X. M., Qian, L. T., Xie, L. J., Liu, H. B., ... & Zeng, X. W. (2021). Down-regulating microRNA-20a regulates CDH1 to protect against cerebral ischemia/reperfusion injury in rats. Cell Cycle, 20(1), 54-64.

Chen, Y. L., Wang, C. Y., Fang, J. H., & Hsu, H. P. (2021). Serine/threonine-protein kinase 24 is an inhibitor of gastric cancer metastasis through suppressing CDH1 gene and enhancing stemness. American journal of cancer research, 11(9), 4277.

Zhai, C., Feng, W., Shi, W., Wang, J., Zhang, Q., Yan, X., ... & Li, M. (2020). Sphingosine-1-phosphate promotes pulmonary artery smooth muscle cells proliferation by stimulating autophagy-mediated E-cadherin/CDH1 down-regulation. European Journal of Pharmacology, 884, 173302.

Rosendo‑Chalma, P., Antonio‑Vejar, V., Bigoni‑Ordóñez, G. D., Patiño‑Morales, C. C., Cano‑García, A., & García‑Carrancá, A. (2020). CDH1 and SNAI1 are regulated by E7 from human papillomavirus types 16 and 18. International journal of oncology, 57(1), 301-313.

Lin, Z. Z., Ming, D. S., Chen, Y. B., Zhang, J. M., Chen, H. H., Jiang, J. J., & Zhang, Z. S. (2019). KMT5A promotes metastasis of clear cell renal cell carcinoma through reducing cadherin‑1 expression. Oncology letters, 17(6), 4907-4913.

Zhao, W., Zhang, L. N., Wang, X. L., Zhang, J., & Yu, H. X. (2019). Long noncoding RNA NSCLCAT1 increases non–small cell lung cancer cell invasion and migration through the Hippo signaling pathway by interacting with CDH1. The FASEB Journal, 33(1), 1151-1166.

Shokraii, F., Moharrami, M., Motamed, N., Shahhoseini, M., Totonchi, M., Ezzatizadeh, V., ... & Ebrahimi, M. (2019). Histone modification marks strongly regulate CDH1 promoter in prostospheres as a model of prostate cancer stem like cells. Cell Journal (Yakhteh), 21(2), 124.

Tania, S. F., Kim, K. R., Suhartono, A. W., Latief, B. S., & Auerkari, E. I. (2018, August). Distribution of E-cadherin 1 (CDH1) promoter methylation in patients with orofacial cleft. In Journal of Physics: Conference Series (Vol. 1073, No. 3, p. 032064). IOP Publishing.

Krempely, K., & Karam, R. (2018). A novel de novo CDH1 germline variant aids in the classification of carboxy-terminal E-cadherin alterations predicted to escape nonsense-mediated mRNA decay. Molecular Case Studies, 4(4), a003012.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant CDH1 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY3672)

Human Recombinant CDH1 protein, ECD, His Tag (CAT#: V2LY-0526-LY3673)

Human Recombinant CDH1 protein, Biotin Conjugated, hFc Tag (CAT#: V2LY-0526-LY3674)

Human Recombinant CDH1 protein, His Tag (CAT#: V2LY-0526-LY3675)

Mouse Recombinant CDH1 protein, His Tag (CAT#: V2LY-0526-LY8215)

Rat Recombinant CDH1 protein, hFc Tag (CAT#: V2LY-0526-LY9339)

Rat Recombinant CDH1 protein, His Tag (CAT#: V2LY-0526-LY9340)

Human CDH1 ELISA Kit (CAT#: V2LY-0626-LY558)

CDH1 Matched Antibody Pair (246) (CAT#: APMAB-246LY)

CDH1 Matched Antibody Pair (247) (CAT#: APMAB-247LY)

Antibody Pairs

CDH1 Matched Antibody Pair (246) (CAT#: APMAB-246LY)

CDH1 Matched Antibody Pair (247) (CAT#: APMAB-247LY)

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Human Recombinant CDH1 protein, ECD, His Tag (CAT#: V2LY-0526-LY3673)

Human Anti-CDH1 Recombinant Antibody (
10H4) (CAT#: V2LY-0725-LY653)

Rabbit Anti-CDH1 Recombinant Antibody (
1E1) (CAT#: V2LY-0725-LY1265)

Rabbit Anti-CDH1 Recombinant Antibody (CBR088G) (CAT#: CBMAB-BT027LY)

Rabbit Anti-CDH1 Recombinant Antibody (CBXC-2658) (CAT#: CBMAB-C4370-CQ)

CDH1 Matched Antibody Pair (246) (CAT#: APMAB-246LY)

Mouse Anti-CDH1 Recombinant Antibody (
29H10) (CAT#: V2LY-0725-LY304)

Mouse Anti-CDH1 Recombinant Antibody (CBT3470) (CAT#: V2LY-0625-LY2512)

Human Recombinant CDH1 protein, Biotin Conjugated, hFc Tag (CAT#: V2LY-0526-LY3674)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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