Cynomolgus Recombinant CD30 protein, His Tag (V2LY-0526-LY1429)

Name: Cynomolgus Recombinant CD30 protein, His Tag
SKU: V2LY-0526-LY1429
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Cynomolgus

Tag

His Tag

Protein Construction

This product is Cynomolgus Recombinant CD30 protein, His Tag consist of Amino Acid: 63-234 and predicts a molecular mass of 22 kDa.

Molecule Mass

22 kDa

Verified

HPLC

Sequence

Amino Acid: 63-234

Species

Cynomolgus

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥95% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC. ≥90% as determined by SEC-MALS(Routinely tested).

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

TNF receptor superfamily member 8

Function

Receptor for TNFSF8/CD30L (PubMed:8391931).
May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (PubMed:8999898).

Biological Process

Biological Process cellular response to mechanical stimulus Source:UniProtKB1 Publication
Biological Process negative regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process positive regulation of TRAIL production Source:UniProtKB1 Publication
Biological Process positive regulation of tumor necrosis factor production Source:UniProtKB1 Publication
Biological Process signal transduction Source:ProtInc1 Publication

Cellular Location

Isoform 1
Cell membrane
Isoform 2
Cytoplasm

Topology

Extracellular: 19-385
Helical: 386-406
Cytoplasmic: 407-595

PTM

Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated (PubMed:8839832).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant CD30 protein, hFc Tag (CAT#: V2LY-0526-LY1428)

Cynomolgus Recombinant CD30 protein, His Tag-1 (CAT#: V2LY-0526-LY1430)

Mouse Recombinant TNFRSF8 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY7989)

Mouse Recombinant TNFRSF8 protein, ECD, His Tag (CAT#: V2LY-0526-LY7990)

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Mouse Anti-TNFRSF8 Recombinant Antibody (CBXC-1745) (CAT#: CBMAB-C4792-CQ)

Cynomolgus Recombinant CD30 protein, hFc Tag (CAT#: V2LY-0526-LY1428)

Mouse Anti-TNFRSF8 Recombinant Antibody (CBYY-C0302) (CAT#: CBMAB-C1008-YY)

Cynomolgus Recombinant CD30 protein, His Tag-1 (CAT#: V2LY-0526-LY1430)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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