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DCN Matched Antibody Pair (323) (APMAB-323LY)

This antibody pair set can be used for detecting and quantifying protein level of human DCN.
See all DCN antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-DCN monoclonal antibody, 100 ug
Detection Antibody
Anti-DCN Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
Alternative Names
Decorin; Bone Proteoglycan II; SLRR1B; PG40; Dermatan Sulphate Proteoglycans II; Small Leucine-Rich Protein 1B; Proteoglycan Core Protein;
Entrez Gene ID
1634
UniProt ID
P07585

Balne, P. K., Gupta, S., Zhang, J., Bristow, D., Faubion, M., Heil, S. D., ... & Mohan, R. R. (2021). The functional role of decorin in corneal neovascularization in vivo. Experimental Eye Research, 207, 108610.

Shibata, S., Shibata, N., Ohtsuka, S., Yoshitomi, Y., Kiyokawa, E., Yonekura, H., ... & Kubo, E. (2021). Role of Decorin in Posterior Capsule Opacification and Eye Lens Development. Cells, 10(4), 863.

Han, B., Li, Q., Wang, C., Chandrasekaran, P., Zhou, Y., Qin, L., ... & Han, L. (2021). Differentiated activities of decorin and biglycan in the progression of post-traumatic osteoarthritis. Osteoarthritis and Cartilage, 29(8), 1181-1192.

Halari, C. D., Nandi, P., Jeyarajah, M. J., Renaud, S. J., & Lala, P. K. (2020). Decorin production by the human decidua: role in decidual cell maturation. Molecular Human Reproduction, 26(10), 784-796.

Reszegi, A., Horváth, Z., Fehér, H., Wichmann, B., Tátrai, P., Kovalszky, I., & Baghy, K. (2020). Protective role of decorin in primary hepatocellular carcinoma. Frontiers in oncology, 10, 645.

Daquinag, A. C., Gao, Z., Fussell, C., Sun, K., & Kolonin, M. G. (2020). Glycosaminoglycan modification of Decorin depends on MMP14 activity and regulates collagen assembly. Cells, 9(12), 2646.

Sainio, A. O., & Järveläinen, H. T. (2019). Decorin‐mediated oncosuppression–a potential future adjuvant therapy for human epithelial cancers. British Journal of Pharmacology, 176(1), 5-15.

Vu, T. T., Marquez, J., Le, L. T., Nguyen, A. T. T., Kim, H. K., & Han, J. (2018). The role of decorin in cardiovascular diseases: more than just a decoration. Free Radical Research, 52(11-12), 1210-1219.

Zhang, W., Ge, Y., Cheng, Q., Zhang, Q., Fang, L., & Zheng, J. (2018). Decorin is a pivotal effector in the extracellular matrix and tumour microenvironment. Oncotarget, 9(4), 5480.

Shen, Y., Russo, V., Zeglinski, M. R., Sellers, S. L., Wu, Z., Oram, C., ... & Granville, D. J. (2017). Recombinant decorin fusion protein attenuates murine abdominal aortic aneurysm formation and rupture. Scientific reports, 7(1), 1-9.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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