EDN1 Matched Antibody Pair (363) (APMAB-363LY)

Name: EDN1 Matched Antibody Pair (363)
SKU: APMAB-363LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-EDN1 monoclonal, IgG2a antibody, 100 ug

Detection Antibody

Anti-EDN1 Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Alternative Names

Endothelin 1; Preproendothelin-1; PPET1; Endothelin-1; ARCND3; HDLCQ7; ET1; QME;

Entrez Gene ID

1906

UniProt ID

P05305

More Infomation

Lazurova, Z., Habalova, V., & Mitro, P. (2022). Association of Polymorphisms in Endothelin-1 and Endothelin Receptor A Genes With Vasovagal Syncope. Physiological Research, 71(1), 93.

Hwang, C. Y., Yu, S. J., Won, J. K., Park, S. M., Noh, H., Lee, S., ... & Cho, K. H. (2022). Systems analysis identifies endothelin 1 axis blockade for enhancing the anti-tumor effect of multikinase inhibitor. Cancer Gene Therapy, 29(6), 845-858.

Hwang, I., Lee, E. J., Park, H., Moon, D., Park, J. N., Kim, K. C., ... & Kim, H. S. (2021). Endothelin-1 enhances the regenerative capability of human bone marrow-derived mesenchymal stem cells in a sciatic nerve injury mouse model. Biomaterials, 275, 120980.

Torres Crigna, A., Link, B., Samec, M., Giordano, F. A., Kubatka, P., & Golubnitschaja, O. (2021). Endothelin-1 axes in the framework of predictive, preventive and personalised (3P) medicine. EPMA Journal, 12(3), 265-305.

Douma, L. G., Solocinski, K., Masten, S. H., Barral, D. H., Barilovits, S. J., Jeffers, L. A., ... & Gumz, M. L. (2020). EDN1-AS, a novel long non-coding RNA regulating endothelin-1 in human proximal tubule cells. Frontiers in Physiology, 11, 209.

Zhang, L., Chen, L., Gao, C., Chen, E., Lightle, A. R., Foulke, L., ... & Zhang, W. (2020). Loss of histone H3 K79 methyltransferase Dot1l facilitates kidney fibrosis by upregulating endothelin 1 through histone deacetylase 2. Journal of the American Society of Nephrology, 31(2), 337-349.

Alcendor, D. J. (2020). Dysregulation of Endothelin-1: Implications for Health Disparities in Alzheimer’s Disease. Journal of Personalized Medicine, 10(4), 199.

Smiianova, Y. O., Pristupa, L. N., Harbuzova, V. Y., & Harbuzova, Y. A. (2019). The association of LYS198ASN-polymorphism of endothelin-1 gene (EDN1) with development of arterial hypertension in ukrainian population. Wiadomosci Lekarskie (Warsaw, Poland: 1960), 72(4), 568-574.

Liang, L. L., Chen, L., Zhou, M. Y., Cai, M. Y., Cheng, J., Chen, Y., ... & Xiong, X. D. (2018). Genetic susceptibility of five tagSNPs in the endothelin-1 (EDN1) gene to coronary artery disease in a Chinese Han population. Bioscience reports, 38(5).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Dog EDN1 ELISA Kit (CAT#: V2LY-0626-LY150)

Human EDN1 ELISA Kit (CAT#: V2LY-0626-LY1510)

Rabbit EDN1 ELISA Kit (CAT#: V2LY-0626-LY288)

Cattle EDN1 ELISA Kit (CAT#: V2LY-0626-LY414)

Pig EDN1 ELISA Kit (CAT#: V2LY-0626-LY588)

Mouse Edn1 ELISA Kit (CAT#: V2LY-0626-LY625)

Rat Edn1 ELISA Kit (CAT#: V2LY-0626-LY897)

Related Products

Mouse Anti-EDN1 (C-terminus) Recombinant Antibody (CBFYE-0443) (CAT#: CBMAB-E0766-FY)

Dog EDN1 ELISA Kit (CAT#: V2LY-0626-LY150)

Mouse Anti-EDN1 Recombinant Antibody (CBFYE-0086) (CAT#: CBMAB-E0181-FY)

Human EDN1 ELISA Kit (CAT#: V2LY-0626-LY1510)

Mouse Anti-EDN1 Recombinant Antibody (CBFYE-0443) (CAT#: V2LY-0425-LY1408)

Mouse Anti-EDN1 (AA 53-211) Recombinant Antibody (CBFYE-0440) (CAT#: CBMAB-E0762-FY)

Mouse Anti-EDN1 Recombinant Antibody (CBFYE-0029) (CAT#: V2LY-0425-LY1403)

Mouse Anti-EDN1 Recombinant Antibody (CBFYE-0086) (CAT#: V2LY-0425-LY1405)

Mouse Anti-EDN1 (AA 113-212) Recombinant Antibody (CBFYE-0441) (CAT#: CBMAB-E0764-FY)

Rat Edn1 ELISA Kit (CAT#: V2LY-0626-LY897)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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