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FGF1 Matched Antibody Pair (429) (APMAB-429LY)

This antibody pair set can be used for detecting and quantifying protein level of human FGF1.
See all FGF1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-FGF1 polyclonal antibody, 100 ug
Detection Antibody
Anti-FGF1 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
Alternative Names
Fibroblast Growth Factor 1; Heparin-Binding Growth Factor 1; Endothelial Cell Growth Factor, Alpha; Endothelial Cell Growth Factor, Beta; Fibroblast Growth Factor 1 (Acidic); HBGF-1; FGF-1; AFGF; FGFA; ECGF;
Entrez Gene ID
2246
UniProt ID
P05230

Gasser, E., Sancar, G., Downes, M., & Evans, R. M. (2022). Metabolic Messengers: fibroblast growth factor 1. Nature Metabolism, 1-9.

Sluzalska, K. D., Slawski, J., Sochacka, M., Lampart, A., Otlewski, J., & Zakrzewska, M. (2021). Intracellular partners of fibroblast growth factors 1 and 2-implications for functions. Cytokine & growth factor reviews, 57, 93-111.

Weant, J., Eveleth, D. D., Subramaniam, A., Jenkins-Eveleth, J., Blaber, M., Li, L., ... & Bradshaw, R. A. (2021). Regenerative responses of rabbit corneal endothelial cells to stimulation by fibroblast growth factor 1 (FGF1) derivatives, TTHX1001 and TTHX1114. Growth Factors, 1-14.

Lin, Q., Huang, Z., Cai, G., Fan, X., Yan, X., Liu, Z., ... & Tan, Y. (2021). Activating adenosine monophosphate–activated protein kinase mediates fibroblast growth factor 1 protection from nonalcoholic fatty liver disease in mice. Hepatology, 73(6), 2206-2222.

Xiao, M., Tang, Y., Lu, G., Guo, Y., Zhang, J., & Gu, J. (2021). Regulatory role of endogenous and exogenous fibroblast growth factor 1 in the cardiovascular system and related diseases. Pharmacological Research, 169, 105596.

Bentsen, M. A., Rausch, D. M., Mirzadeh, Z., Muta, K., Scarlett, J. M., Brown, J. M., ... & Pers, T. H. (2020). Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission. Nature communications, 11(1), 1-16.

Xu, Z., Wu, Y., Wang, F., Li, X., Wang, P., Li, Y., ... & Liu, Y. (2020). Fibroblast growth factor 1 ameliorates diabetes-induced liver injury by reducing cellular stress and restoring autophagy. Frontiers in Pharmacology, 11, 52.

Xu, Z., Zhou, X., & Chen, G. (2019). Expression and mechanism of interleukin 1 (IL-1), interleukin 2 (IL-2), interleukin 8 (IL-8), BMP, fibroblast growth factor 1 (FGF1), and insulin-like growth factor (IGF-1) in lumbar disc herniation. Medical science monitor: international medical journal of experimental and clinical research, 25, 984.

Fan, L., Ding, L., Lan, J., Niu, J., He, Y., & Song, L. (2019). Fibroblast growth factor-1 improves insulin resistance via repression of JNK-mediated inflammation. Frontiers in pharmacology, 10, 1478.

Wu, Y., Li, Y., Jiang, T., Yuan, Y., Li, R., Xu, Z., ... & Xiao, J. (2018). Reduction of cellular stress is essential for Fibroblast growth factor 1 treatment for diabetic nephropathy. Journal of Cellular and Molecular Medicine, 22(12), 6294-6303.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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