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HSPA1L Matched Antibody Pair (576) (APMAB-576LY)

This antibody pair set can be used for detecting and quantifying protein level of human HSPA1L.
See all HSPA1L antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-HSPA1L polyclonal antibody, 100 ug
Detection Antibody
Anti-HSPA1L Mouse polyclonal antibody, 40 ul
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008]
Alternative Names
Heat Shock Protein Family A (Hsp70) Member 1 Like; Heat Shock 70kDa Protein 1-Like; Heat Shock 70 KDa Protein 1-Hom; Heat Shock 70kD Protein-Like 1; Heat Shock 70 KDa Protein 1L; HSP70-HOM;
Entrez Gene ID
3305
UniProt ID
P34931

Liu, X., Teng, Z., Wang, Z., Zhu, P., Song, Z., & Liu, F. (2022). Expressions of HSPA1L and HSPA9 are associated with poor sperm quality of low‐motility spermatozoa in fertile men. Andrologia, 54(2), e14321.

Muhammad, J. S., Saheb Sharif-Askari, N., Cui, Z. G., Hamad, M., & Halwani, R. (2021). SARS-CoV-2 infection-induced promoter hypomethylation as an epigenetic modulator of heat shock protein A1L (HSPA1L) gene. Frontiers in Genetics, 12, 622271.

Nakatsuka, A., Yamaguchi, S., Eguchi, J., Kakuta, S., Iwakura, Y., Sugiyama, H., & Wada, J. (2021). A Vaspin–HSPA1L complex protects proximal tubular cells from organelle stress in diabetic kidney disease. Communications Biology, 4(1), 373.

Lee, J. H., Yoon, Y. M., Song, K. H., Noh, H., & Lee, S. H. (2020). Melatonin suppresses senescence‐derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L–mitophagy pathway. Aging cell, 19(3), e13111.

Wang, X., Xie, W., Yao, Y., Zhu, Y., Zhou, J., Cui, Y., ... & Liu, M. (2020). The heat shock protein family gene Hspa1l in male mice is dispensable for fertility. PeerJ, 8, e8702.

De Andrade, W. P., Braga, L. D. C., Goncales, N. G., Silva, L. M., & Da Silva Filho, A. L. (2020). HSPA1A, HSPA1L and TRAP1 heat shock genes may be associated with prognosis in ovarian epithelial cancer. Oncology Letters, 19(1), 359-367.

Choi, S. I., Lee, J. H., Kim, R. K., Jung, U., Kahm, Y. J., Cho, E. W., & Kim, I. G. (2020). HSPA1L enhances cancer stem cell-like properties by activating IGF1Rβ and regulating β-catenin transcription. International Journal of Molecular Sciences, 21(18), 6957.

Williams, P. A., Kobilnyk, H. E., McMillan, E. A., & Strochlic, T. I. (2019). MAPKAP kinase 2–mediated phosphorylation of HspA1L protects male germ cells from heat stress–induced apoptosis. Cell Stress and Chaperones, 24, 1127-1136.

Kohan, L., Tabiee, O., & Sepahi, N. (2019). HSPA1L and HSPA1B gene polymorphisms and haplotypes are associated with idiopathic male infertility in Iranian population. European Journal of Obstetrics & Gynecology and Reproductive Biology, 240, 57-61.

Huusko, J. M., Karjalainen, M. K., Graham, B. E., Zhang, G., Farrow, E. G., Miller, N. A., ... & Muglia, L. J. (2018). Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth. PLoS genetics, 14(7), e1007394.

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For research use only. Not intended for any clinical use.

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