Human NRSN2 ELISA Kit (V2LY-0626-LY4941)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0095 ng/mL
Detection Range
0.02-4.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
22.0 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Neurensin 2
Function
May play a role in maintenance and/or transport of vesicles.
Biological Process
Nervous system developmentManual Assertion Based On ExperimentIBA:GO_Central

Ren, S., Chen, M., Chen, Y., & Ding, K. (2023). NRSN2 is a Prognostic Biomarker in Gastric Cancer and Facilitates the Growth and Migration of Gastric Cancer Cells. Protein and Peptide Letters, 30(5), 427-438.

Wu, Y. B., Li, S. Y., Liu, J. Y., Xue, J. J., Xu, J. F., Chen, T., ... & Shen, C. (2023). Long non-coding RNA NRSN2-AS1 promotes ovarian cancer progression through targeting PTK2/β-catenin pathway. Cell Death & Disease, 14(10), 696.

Keremu, A., Aila, P., Tusun, A., Abulikemu, M., & Zou, X. (2022). Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway. European Journal of Histochemistry: EJH, 66(3).

Chen, Q., Xie, J., & Yang, Y. (2022). Long non-coding RNA NRSN2-AS1 facilitates tumorigenesis and progression of ovarian cancer via miR-744-5p/PRKX axis. Biology of Reproduction, 106(3), 526-539.

Xu, T., Yan, Z., Lu, J., Chen, L., Li, X., Li, Y., ... & Guo, W. (2022). Long non-coding RNA NRSN2-AS1, transcribed by SOX2, promotes progression of esophageal squamous cell carcinoma by regulating the ubiquitin-degradation of PGK1. Clinical & Experimental Metastasis, 39(5), 757-769.

Yan, Z., Xu, T., Lu, J., Wu, Z., Li, X., Xu, J., ... & Dong, Z. (2022). E2F1-activated NRSN2 promotes esophageal squamous cell carcinoma progression through AKT/mTOR pathway. Pathology-Research and Practice, 236, 153963.

Li, F., Chen, X., Shang, C., Ying, Q., Zhou, X., Zhu, R., ... & Jiang, Z. (2021). Bone marrow mesenchymal stem cells-derived extracellular vesicles promote proliferation, invasion and migration of osteosarcoma cells via the lncRNA MALAT1/miR-143/NRSN2/Wnt/β-catenin axis. OncoTargets and therapy, 737-749.

Zhou, J., Xu, L., Yang, P., Lu, Y., Lin, S., & Yuan, G. (2021). The exosomal transfer of human bone marrow mesenchymal stem cell-derived miR-1913 inhibits osteosarcoma progression by targeting NRSN2. American Journal of Translational Research, 13(9), 10178.

Ren, F., Zhang, W., Lu, S., Ren, H., & Guo, Y. (2020). NRSN2 promotes breast cancer metastasis by activating PI3K/AKT/mTOR and NF‑κB signaling pathways. Oncology Letters, 19(1), 813-823.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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