Human Recombinant ROR2 protein, ECD, Biotin Conjugated, His & AVI Tag (V2LY-0526-LY6592)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073).
In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).
Biological Process bone mineralizationIEA:Ensembl
Biological Process macrophage migrationIEA:Ensembl
Biological Process male genitalia developmentIEA:Ensembl
Biological Process positive regulation of cell migrationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of JUN kinase activityIEA:Ensembl
Biological Process positive regulation of kinase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of macrophage differentiationIEA:Ensembl
Biological Process positive regulation of neuron projection developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of phosphatidylinositol 3-kinase signalingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of protein kinase C activityIEA:Ensembl
Biological Process positive regulation of synaptic transmission, glutamatergicIEA:Ensembl
Biological Process signal transductionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process transmembrane receptor protein tyrosine kinase signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
A form of brachydactyly. Brachydactyly defines a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals. In brachydactyly type B1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent. Both fingers and toes are affected. The thumbs and big toes are usually deformed. Symphalangism is also a feature.
Robinow syndrome, autosomal recessive 1 (RRS1):
A recessive form of Robinow syndrome, a disease characterized by short-limb dwarfism, costovertebral segmentation defects and abnormalities of the head, face and external genitalia. The clinical signs are generally far more severe in recessive cases, particularly skeletal abnormalities. All patients with the recessive form suffer from vertebral segmentation abnormalities, resulting in scoliosis and chest deformities. Rib fusions are considered to be characteristic of the autosomal recessive form. Patients can also present brachydactyly, with extensive aplasia/hypoplasia of the phalanges and metacarpals/metatarsals, and brachy-syn-polydactyly of the hands and oligodactyly of the feet.
Helical: 404-424
Cytoplasmic: 425-943
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Mouse Anti-Ror2 Recombinant Antibody (CAT#: CBMAB-0650-LY)
Human Recombinant ROR2, Active protein, GST Tag (CAT#: V2LY-0526-LY6594)
Mouse Recombinant ROR2 protein, His Tag (CAT#: V2LY-0526-LY8844)
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Mouse Recombinant ROR2 protein, His Tag (CAT#: V2LY-0526-LY8844)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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