Human Recombinant RRM2B protein, His Tag (V2LY-0526-LY5934)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Biological Process deoxyribonucleoside triphosphate metabolic processIEA:Ensembl
Biological Process deoxyribonucleotide biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process DNA repairManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process DNA synthesis involved in DNA repair1 PublicationIC:ComplexPortal
Biological Process kidney developmentIEA:Ensembl
Biological Process mitochondrial DNA replicationManual Assertion Based On ExperimentIMP:ComplexPortal
Biological Process negative regulation of intrinsic apoptotic signaling pathway by p53 class mediatorIEA:Ensembl
Biological Process positive regulation of G0 to G1 transitionManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process positive regulation of G2/M transition of mitotic cell cycleManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process renal system processIEA:Ensembl
Biological Process response to amineIEA:Ensembl
Biological Process response to oxidative stressIEA:Ensembl
Biological Process ribonucleoside diphosphate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Nucleus
Translocates from cytoplasm to nucleus in response to DNA damage.
A disorder due to mitochondrial dysfunction characterized by various combinations of neonatal hypotonia, neurological deterioration, respiratory distress, lactic acidosis, and renal tubulopathy.
Mitochondrial DNA depletion syndrome 8B (MTDPS8B):
A disease due to mitochondrial dysfunction and characterized by ophthalmoplegia, ptosis, gastrointestinal dysmotility, cachexia, peripheral neuropathy.
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant, 5 (PEOA5):
A disorder characterized by progressive weakness of ocular muscles and levator muscle of the upper eyelid. In a minority of cases, it is associated with skeletal myopathy, which predominantly involves axial or proximal muscles and which causes abnormal fatigability and even permanent muscle weakness. Ragged-red fibers and atrophy are found on muscle biopsy. A large proportion of chronic ophthalmoplegias are associated with other symptoms, leading to a multisystemic pattern of this disease. Additional symptoms are variable, and may include cataracts, hearing loss, sensory axonal neuropathy, ataxia, depression, hypogonadism, and parkinsonism.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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