Human Recombinant SERPING1 protein, His Tag (V2LY-0526-LY2451)

See all SERPING1 antibodies
Go to compare Compare Online Inquiry
Datasheet
SDS
Request for COA
Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host
HEK293 Cells
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant SERPING1 protein, His Tag consist of Amino Acid: 1-500 and predicts a molecular mass of 54.3 kDa.
Molecule Mass
54.3 kDa
Verified
HPLC
Sequence
Amino Acid: 1-500
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
≥95% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC.
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
Tris, NaCl, Glycerol
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
Serpin Family G Member 1
Function
Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.
Biological Process
Biological Process agingIEA:Ensembl
Biological Process blood circulationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process blood coagulationIEA:UniProtKB-KW
Biological Process complement activation, classical pathwayIEA:UniProtKB-KW
Biological Process fibrinolysisIEA:UniProtKB-KW
Biological Process innate immune responseIEA:UniProtKB-KW
Biological Process negative regulation of complement activation, lectin pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
Involvement in disease
Angioedema, hereditary (HAE):
An autosomal dominant disorder characterized by episodic local swelling involving subcutaneous or submucous tissue of the upper respiratory and gastrointestinal tracts, face, extremities, and genitalia. Hereditary angioedema due to C1 esterase inhibitor deficiency is comprised of two clinically indistinguishable forms. In hereditary angioedema type 1, serum levels of C1 esterase inhibitor are decreased, while in type 2, the levels are normal or elevated, but the protein is non-functional.
PTM
Highly glycosylated (49%) with N- and O-glycosylation. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan heterogeneity at Asn-25: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (minor), Hex6HexNAc5 (major) and dHex1Hex6HexNAc5 (minor).
Can be proteolytically cleaved by E.coli stcE.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Human Recombinant SERPING1 protein, His Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rat Recombinant SERPING1 protein, His Tag (CAT#: V2LY-0526-LY9187)

SERPING1 Matched Antibody Pair (1074) (CAT#: APMAB-1074LY)

Antibody Pairs

SERPING1 Matched Antibody Pair (1074) (CAT#: APMAB-1074LY)

Related Products

Mouse Anti-SERPING1 Recombinant Antibody (CBXS-5612) (CAT#: CBMAB-S0490-CQ)

SERPING1 Matched Antibody Pair (1074) (CAT#: APMAB-1074LY)

Mouse Anti-SERPING1 Recombinant Antibody (CAP282) (CAT#: CBMAB-AP706LY)

Rabbit Anti-SERPING1 Recombinant Antibody (18) (CAT#: CBMAB-C3442-LY)

Mouse Anti-SERPING1 Recombinant Antibody (CBXS-5293) (CAT#: CBMAB-S2507-CQ)

Mouse Anti-SERPING1 Recombinant Antibody (KT28) (CAT#: CBMAB-S6393-CQ)

Mouse Anti-SERPING1 Recombinant Antibody (CBXS-0262) (CAT#: CBMAB-S3239-CQ)

Mouse Anti-SERPING1 Recombinant Antibody (8F3) (CAT#: CBMAB-C9182-LY)

Mouse Anti-SERPING1 Recombinant Antibody (CBXS-1792) (CAT#: CBMAB-S4608-CQ)

Rat Recombinant SERPING1 protein, His Tag (CAT#: V2LY-0526-LY9187)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry
Request bulk or custom quote Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.