Human Recombinant SFTPB protein, ECD, His Tag (V2LY-0526-LY6749)

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host
CHO Cells
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant SFTPB protein, ECD, His Tag consist of Amino Acid: 25-381 and predicts a molecular mass of 41.04 kDa.
Molecule Mass
41.04 kDa
Protein Domain
ECD
Sequence
Amino Acid: 25-381
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
≥95% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
Surfactant Protein B
Function
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
Biological Process
Biological Process animal organ morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Biological Process respiratory gaseous exchange by respiratory systemManual Assertion Based On ExperimentTAS:ProtInc
Biological Process sphingolipid metabolic processIEA:InterPro
Cellular Location
Secreted, extracellular space, surface film
Involvement in disease
Pulmonary surfactant metabolism dysfunction 1 (SMDP1):
A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
Respiratory distress syndrome in premature infants (RDS):
A lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called 'hyaline membranes'.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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