Human Recombinant ST14 protein (V2LY-0526-LY6953)

Name: Human Recombinant ST14 protein
SKU: V2LY-0526-LY6953
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Protein Construction

This product is Human Recombinant ST14 protein consist of Amino Acid: 615-855 and predicts a molecular mass of 26.44 kDa.

Molecule Mass

26.44 kDa

Sequence

Amino Acid: 615-855

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥90% as determined by SDS-PAGE.

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

suppression of tumorigenicity 14 (colon carcinoma)

Function

Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing.

Biological Process

Biological Process epithelial cell morphogenesis involved in placental branchingIEA:Ensembl
Biological Process keratinocyte differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process neural tube closureIEA:Ensembl
Biological Process protein catabolic processIEA:Ensembl
Biological Process proteolysisManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Membrane

Involvement in disease

Ichthyosis, congenital, autosomal recessive 11 (ARCI11):
A form of autosomal recessive congenital ichthyosis, a disorder of keratinization with abnormal differentiation and desquamation of the epidermis, resulting in abnormal skin scaling over the whole body. The main skin phenotypes are lamellar ichthyosis (LI) and non-bullous congenital ichthyosiform erythroderma (NCIE), although phenotypic overlap within the same patient or among patients from the same family can occur. Lamellar ichthyosis is a condition often associated with an embedment in a collodion-like membrane at birth; skin scales later develop, covering the entire body surface. Non-bullous congenital ichthyosiform erythroderma characterized by fine whitish scaling on an erythrodermal background; larger brownish scales are present on the buttocks, neck and legs.

Topology

Cytoplasmic: 1-55
Helical: 56-76
Extracellular: 77-855

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human ST14 ELISA Kit (CAT#: V2LY-0626-LY5293)

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Mouse Anti-ST14 Recombinant Antibody (CBFYM-3141) (CAT#: CBMAB-M3338-FY)

Human ST14 ELISA Kit (CAT#: V2LY-0626-LY5293)

Mouse Anti-ST14 Recombinant Antibody (CBXS-2507) (CAT#: CBMAB-S5264-CQ)

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Mouse Anti-ST14 (AA 619-854) Recombinant Antibody (CBFYM-3142) (CAT#: CBMAB-M3339-FY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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