Human SLC12A5 ELISA Kit (V2LY-0626-LY5492)

Go to compare Compare Online Inquiry
Tested Data
Request for COA
Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.007 ng/mL
Detection Range
0.015-3 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
126.2 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Solute Carrier Family 12 Member 5
Function
Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl- homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl- levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition (By similarity).
Involved in the regulation of dendritic spine formation and maturation (PubMed:24668262).
Biological Process
Biological Process cell volume homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cellular chloride ion homeostasisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular ion homeostasisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process chloride ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process chloride transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process dendritic spine developmentManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process hypotonic responseManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process intracellular pH reductionIEA:Ensembl
Biological Process ion transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process learningIEA:Ensembl
Biological Process multicellular organism growthIEA:Ensembl
Biological Process potassium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process potassium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process thermosensory behaviorIEA:Ensembl
Cellular Location
Membrane
Involvement in disease
Developmental and epileptic encephalopathy 34 (DEE34):
A form of epileptic encephalopathy, a heterogeneous group of severe early-onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. DEE34 is characterized by onset of refractory migrating focal seizures in infancy. Affected children show developmental regression and are severely impaired globally.
Epilepsy, idiopathic generalized 14 (EIG14):
An autosomal dominant form of idiopathic generalized epilepsy, a disorder characterized by recurring generalized seizures in the absence of detectable brain lesions and/or metabolic abnormalities. Generalized seizures arise diffusely and simultaneously from both hemispheres of the brain. Seizure types include juvenile myoclonic seizures, absence seizures, and generalized tonic-clonic seizures.
Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Human SLC12A5 ELISA Kit?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.