Human SLC19A3 ELISA Kit (V2LY-0626-LY3505)

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Tested Data
Request for COA
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Basic Information

Sensitivity
0.046 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
55.7 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
solute carrier family 19, member 3
Function
Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity.
Biological Process
Biological Process thiamine transmembrane transportISS:BHF-UCL
Biological Process thiamine transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process thiamine-containing compound metabolic processTAS:Reactome
Biological Process transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Involvement in disease
Thiamine metabolism dysfunction syndrome 2, biotin- or thiamine-responsive type (THMD2):
An autosomal recessive metabolic disorder characterized by episodic encephalopathy, often triggered by febrile illness, presenting as confusion, seizures, external ophthalmoplegia, dysphagia, and sometimes coma and death. If untreated, encephalopathies can result in permanent dystonia. Brain imaging may show characteristic bilateral lesions of the basal ganglia.
Topology
Cytoplasmic: 1-7
Helical: 8-28
Extracellular: 29-53
Helical: 54-74
Cytoplasmic: 75-81
Helical: 82-102
Extracellular: 103-110
Helical: 111-131
Cytoplasmic: 132-144
Helical: 145-165
Extracellular: 166-169
Helical: 170-190
Cytoplasmic: 191-282
Helical: 283-303
Extracellular: 304-316
Helical: 317-337
Cytoplasmic: 338-342
Helical: 343-363
Extracellular: 364-375
Helical: 376-396
Cytoplasmic: 397-405
Helical: 406-426
Extracellular: 427-434
Helical: 435-455
Cytoplasmic: 456-496
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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