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IFITM3 Matched Antibody Pair (595) (APMAB-595LY)


See all IFITM3 antibodies
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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-IFITM3 monoclonal antibody, 100 ug
Detection Antibody
Anti-IFITM3 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012]
Alternative Names
Interferon Induced Transmembrane Protein 3
Entrez Gene ID
10410
UniProt ID
Q01628
More Infomation

Schönfelder, K., Breuckmann, K., Elsner, C., Dittmer, U., Fistera, D., Herbstreit, F., ... & Möhlendick, B. (2021). The influence of IFITM3 polymorphisms on susceptibility to SARS-CoV-2 infection and severity of COVID-19. Cytokine, 142, 155492.

Ahi, Y. S., Yimer, D., Shi, G., Majdoul, S., Rahman, K., Rein, A., & Compton, A. A. (2020). IFITM3 reduces retroviral envelope abundance and function and is counteracted by glycoGag. MBio, 11(1), 10-1128.

Lee, J., Robinson, M. E., Ma, N., Artadji, D., Ahmed, M. A., Xiao, G., ... & Müschen, M. (2020). IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells. Nature, 588(7838), 491-497.

Rajapaksa, U. S., Jin, C., & Dong, T. (2020). Malignancy and IFITM3: friend or foe?. Frontiers in Oncology, 10, 593245.

Hur, J. Y., Frost, G. R., Wu, X., Crump, C., Pan, S. J., Wong, E., ... & Li, Y. M. (2020). The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease. Nature, 586(7831), 735-740.

Wellington, D., Laurenson-Schafer, H., Abdel-Haq, A., & Dong, T. (2019). IFITM3: How genetics influence influenza infection demographically. Biomedical journal, 42(1), 19-26.

Spence, J. S., He, R., Hoffmann, H. H., Das, T., Thinon, E., Rice, C. M., ... & Hang, H. C. (2019). IFITM3 directly engages and shuttles incoming virus particles to lysosomes. Nature chemical biology, 15(3), 259-268.

Campbell, R. A., Schwertz, H., Hottz, E. D., Rowley, J. W., Manne, B. K., Washington, A. V., ... & Rondina, M. T. (2019). Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3. Blood, The Journal of the American Society of Hematology, 133(19), 2013-2026.

Kenney, A. D., McMichael, T. M., Imas, A., Chesarino, N. M., Zhang, L., Dorn, L. E., ... & Yount, J. S. (2019). IFITM3 protects the heart during influenza virus infection. Proceedings of the National Academy of Sciences, 116(37), 18607-18612.

Zani, A., & Yount, J. S. (2018). Antiviral protection by IFITM3 in vivo. Current clinical microbiology reports, 5, 229-237.

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For research use only. Not intended for any clinical use.

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