IL17F Matched Antibody Pair (619) (APMAB-619LY)

Name: IL17F Matched Antibody Pair (619)
SKU: APMAB-619LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-IL17F monoclonal, IgG2a antibody, 100 ug

Detection Antibody

Anti-IL17F Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]

Alternative Names

Interleukin 17F

Entrez Gene ID

112744

UniProt ID

Q96PD4

More Infomation

Tam, H. K. J., Robinson, P. C., & Nash, P. (2022). Inhibiting IL-17A and IL-17F in rheumatic disease: Therapeutics help to elucidate disease mechanisms. Current Rheumatology Reports, 24(10), 310-320.

Braga, M., Lara-Armi, F. F., Neves, J. S. F., Rocha-Loures, M. A., Terron-Monich, M. D. S., Bahls-Pinto, L. D., ... & Visentainer, J. E. L. (2021). Influence of IL10 (rs1800896) polymorphism and TNF-α, IL-10, IL-17A, and IL-17F serum levels in ankylosing spondylitis. Frontiers in immunology, 12, 653611.

Iznardo, H., & Puig, L. (2021). Dual inhibition of IL-17A and IL-17F in psoriatic disease. Therapeutic Advances in Chronic Disease, 12, 20406223211037846.

Adams, R., Maroof, A., Baker, T., Lawson, A. D., Oliver, R., Paveley, R., ... & Griffiths, M. (2020). Bimekizumab, a novel humanized IgG1 antibody that neutralizes both IL-17A and IL-17F. Frontiers in Immunology, 11, 1894.

Goepfert, A., Lehmann, S., Blank, J., Kolbinger, F., & Rondeau, J. M. (2020). Structural analysis reveals that the cytokine IL-17F forms a homodimeric complex with receptor IL-17RC to drive IL-17RA-independent signaling. Immunity, 52(3), 499-512.

Gao, S., Mao, C., Cheng, J., Deng, Q., & Sheng, W. (2020). Association of IL‐17A‐197G/A and IL‐17F‐7488T/C polymorphisms and osteoarthritis susceptibility: A meta‐analysis. International Journal of Rheumatic Diseases, 23(1), 37-46.

Burns, L. A., Maroof, A., Marshall, D., Steel, K. J., Lalnunhlimi, S., Cole, S., ... & Taams, L. S. (2020). Presence, function, and regulation of IL‐17F‐expressing human CD4+ T cells. European Journal of Immunology, 50(4), 568-580.

Chen, Y., Chen, Y., Cao, P., Su, W., Zhan, N., & Dong, W. (2020). Fusobacterium nucleatum facilitates ulcerative colitis through activating IL‐17F signaling to NF‐κB via the upregulation of CARD3 expression. The Journal of pathology, 250(2), 170-182.

Glatt, S., Baeten, D., Baker, T., Griffiths, M., Ionescu, L., Lawson, A. D., ... & Shaw, S. (2018). Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation. Annals of the rheumatic diseases, 77(4), 523-532.

Tang, C., Kakuta, S., Shimizu, K., Kadoki, M., Kamiya, T., Shimazu, T., ... & Iwakura, Y. (2018). Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota. Nature Immunology, 19(7), 755-765.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus, Rhesus Recombinant IL17F protein, His Tag (CAT#: V2LY-0526-LY1719)

Human Recombinant IL17F protein (CAT#: V2LY-0526-LY4774)

Human Recombinant IL17F protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY4775)

Human Recombinant IL17F protein, His Tag (CAT#: V2LY-0526-LY4776)

Human Recombinant IL17F protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY4777)

Mouse Recombinant IL17F protein (CAT#: V2LY-0526-LY8491)

Mouse Recombinant IL17F protein, His Tag (CAT#: V2LY-0526-LY8492)

Rat Recombinant IL17F protein, His Tag (CAT#: V2LY-0526-LY9443)

Related Products

Mouse Anti-IL17F Recombinant Antibody (CBYY-I0720) (CAT#: CBMAB-I1608-YY)

Human Recombinant IL17F protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY4775)

Cynomolgus, Rhesus Recombinant IL17F protein, His Tag (CAT#: V2LY-0526-LY1719)

Mouse Recombinant IL17F protein, His Tag (CAT#: V2LY-0526-LY8492)

Mouse Anti-IL17F Recombinant Antibody (CF224) (CAT#: CBMAB-FT266LY)

Mouse Anti-IL17F Recombinant Antibody (4H1629) (CAT#: CBMAB-I1356-YY)

Mouse Anti-IL17F Recombinant Antibody (CBYY-I0792) (CAT#: CBMAB-I1765-YY)

Mouse Anti-IL17F Recombinant Antibody (CBFYM-1145) (CAT#: CBMAB-M1302-FY)

Mouse Anti-IL17F Recombinant Antibody (B-G46) (CAT#: CBMAB-I2011-YY)

Human Recombinant IL17F protein (CAT#: V2LY-0526-LY4774)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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