IL1A Matched Antibody Pair (621) (APMAB-621LY)

Name: IL1A Matched Antibody Pair (621)
SKU: APMAB-621LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-IL1A monoclonal antibody, 100 ug

Detection Antibody

Anti-IL1A Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]

Alternative Names

Interleukin 1 Alpha

Entrez Gene ID

3552

UniProt ID

P01583

More Infomation

Maculewicz, E., Antkowiak, B., Antkowiak, O., Borecka, A., Mastalerz, A., Leońska-Duniec, A., ... & Cięszczyk, P. (2022). The interactions between interleukin-1 family genes: IL1A, IL1B, IL1RN, and obesity parameters. BMC genomics, 23(1), 1-12.

Leon, K. E., Buj, R., Lesko, E., Dahl, E. S., Chen, C. W., Tangudu, N. K., ... & Aird, K. M. (2021). DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A. Journal of Cell Biology, 220(8), e202008101.

Harati-Sadegh, M., Sargazi, S., Khorasani, M., Ansari-Moghaddam, A., Mirinejad, S., Sheervalilou, R., & Saravani, R. (2021). IL1A and IL1B gene polymorphisms and keratoconus susceptibility: evidence from an updated meta-analysis. Ophthalmic Genetics, 42(5), 503-513.

Li, M., Yang, J., Liu, K., Yang, J., Zhan, X., Wang, L., ... & Mao, Z. (2020). p16 promotes proliferation in cervical carcinoma cells through CDK6-HuR-IL1A axis. Journal of Cancer, 11(6), 1457.

Xia, H., Chen, Y., Meng, J., & Liang, C. (2019). Effect of polymorphism on IL1A to cancer susceptibility: Evidence based on 34,016 subjects. Artificial cells, nanomedicine, and biotechnology, 47(1), 3138-3152.

Li, H., Duan, N., Zhang, Q., & Shao, Y. (2019). IL1A & IL1B genetic polymorphisms are risk factors for thyroid cancer in a Chinese Han population. International Immunopharmacology, 76, 105869.

Ji, H., Lu, L., Huang, J., Liu, Y., Zhang, B., Tang, H., ... & Lu, H. (2019). IL1A polymorphisms is a risk factor for colorectal cancer in Chinese Han population: a case control study. BMC cancer, 19(1), 1-8.

Hashemi, M., Bahari, G., Sarhadi, S., Eskandari, E., Narouie, B., Taheri, M., & Ghavami, S. (2018). 4‐bp insertion/deletion (rs3783553) polymorphism within the 3′ UTR of IL1A contributes to the risk of prostate cancer in a sample of Iranian population. Journal of cellular biochemistry, 119(3), 2627-2635.

Tanaka, Y., Uchi, H., Hashimoto-Hachiya, A., & Furue, M. (2018). Tryptophan photoproduct FICZ upregulates IL1A, IL1B, and IL6 expression via oxidative stress in keratinocytes. Oxidative medicine and cellular longevity, 2018.

Oliveira, M. B., de Vasconcellos, J. P. C., Ananina, G., Costa, V. P., & de Melo, M. B. (2018). Association between IL1A and IL1B polymorphisms and primary open angle glaucoma in a Brazilian population. Experimental Biology and Medicine, 243(13), 1083-1091.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

IL1A Matched Antibody Pair (620) (CAT#: APMAB-620LY)

IL1A Matched Antibody Pair (622) (CAT#: APMAB-622LY)

Canine Recombinant IL1A protein (CAT#: V2LY-0526-LY1263)

Cynomolgus Recombinant IL1A protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY1544)

Human Recombinant IL1A protein (CAT#: V2LY-0526-LY4705)

Human Recombinant IL1A protein-1 (CAT#: V2LY-0526-LY4706)

Mouse Recombinant IL1A protein (CAT#: V2LY-0526-LY8454)

Rabbit Recombinant IL1A protein (CAT#: V2LY-0526-LY9127)

Rat Recombinant IL1A protein (CAT#: V2LY-0526-LY9431)

Antibody Pairs

IL1A Matched Antibody Pair (620) (CAT#: APMAB-620LY)

IL1A Matched Antibody Pair (622) (CAT#: APMAB-622LY)

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Isotype control

For research use only. Not intended for any clinical use.

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