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ITGB2 Matched Antibody Pair (651) (APMAB-651LY)

This antibody pair set can be used for detecting and quantifying protein level of human ITGB2.
See all ITGB2 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-ITGB2 monoclonal antibody, 100 ug
Detection Antibody
Anti-ITGB2 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Alternative Names
Integrin Subunit Beta 2
Entrez Gene ID
3689
UniProt ID
P05107

Liu, H., Wang, J., Luo, T., Zhen, Z., Liu, L., Zheng, Y., ... & Hu, X. (2023). Correlation between ITGB2 expression and clinical characterization of glioma and the prognostic significance of its methylation in low-grade glioma (LGG). Frontiers in endocrinology, 13, 1106120.

Xu, H., Zhang, A., Han, X., Li, Y., Zhang, Z., Song, L., ... & Lou, M. (2022). ITGB2 as a prognostic indicator and a predictive marker for immunotherapy in gliomas. Cancer Immunology, Immunotherapy, 1-16.

Zu, L., He, J., Zhou, N., Zeng, J., Zhu, Y., Tang, Q., ... & Xu, S. (2022). The profile and clinical significance of ITGB2 expression in non-Small-Cell lung cancer. Journal of Clinical Medicine, 11(21), 6421.

Sun, Z., Dang, Q., Liu, Z., Shao, B., Chen, C., Guo, Y., ... & Yuan, W. (2021). LINC01272/miR-876/ITGB2 axis facilitates the metastasis of colorectal cancer via epithelial-mesenchymal transition. Journal of Cancer, 12(13), 3909.

Wei, J., Huang, X. J., Huang, Y., Xiong, M. Y., Yao, X. Y., Huang, Z. N., ... & Cheng, P. (2021). Key immune-related gene ITGB2 as a prognostic signature for acute myeloid leukemia. Annals of Translational Medicine, 9(17).

George, L., Menden, H., Xia, S., Yu, W., Holmes, A., Johnston, J., ... & Sampath, V. (2021). ITGB2 (Integrin β2) immunomodulatory gene variants in premature infants with necrotizing enterocolitis. Journal of pediatric gastroenterology and nutrition, 72(2), e37-e41.

Li, J., Zhang, Z., Feng, X., Shen, Z., Sun, J., Zhang, X., ... & Wang, Z. (2021). Stanniocalcin-2 promotes cell EMT and glycolysis via activating ITGB2/FAK/SOX6 signaling pathway in nasopharyngeal carcinoma. Cell Biology and Toxicology, 1-14.

Yang, M., Qin, Q., Zhu, J., Guo, Y., Yin, T., Wu, H., & Wang, C. (2020). Long noncoding RNA ITGB2‐AS1 promotes growth and metastasis through miR‐4319/RAF1 axis in pancreatic ductal adenocarcinoma. Journal of Cellular Physiology.

Dai, J., Xu, L. J., Han, G. D., Jiang, H. T., Sun, H. L., Zhu, G. T., & Tang, X. M. (2018). Down-regulation of long non-coding RNA ITGB2-AS1 inhibits osteosarcoma proliferation and metastasis by repressing Wnt/β-catenin signalling and predicts favourable prognosis. Artificial cells, nanomedicine, and biotechnology, 46(sup3), 783-790.

Liu, M., Gou, L., Xia, J., Wan, Q., Jiang, Y., Sun, S., ... & Zhang, Y. (2018). LncRNA ITGB2-AS1 could promote the migration and invasion of breast cancer cells through up-regulating ITGB2. International journal of molecular sciences, 19(7), 1866.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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