MCM4 Matched Antibody Pair (725) (APMAB-725LY)

Name: MCM4 Matched Antibody Pair (725)
SKU: APMAB-725LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-MCM4 polyclonal antibody, 100 ug

Detection Antibody

Anti-MCM4 Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

Alternative Names

Minichromosome Maintenance Complex Component 4; CDC21 Homolog; P1-CDC21; CDC21; MCM4 Minichromosome Maintenance Deficient 4 (S. Cerevisiae); Homolog Of S. Pombe Cell Devision Cycle 21; Minichromosome Maintenance Deficient 4;

Entrez Gene ID

4173

UniProt ID

P33991

More Infomation

Katsuya, N., Ishikawa, A., Kido, A., Fukui, T., Kobayashi, G., Sekino, Y., ... & Oue, N. (2023). Minichromosome maintenance 4 is associated with cancer stemness and poor survival of patients with gastric cancer. Pathobiology, 90(3), 147-154.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

MCM4 Matched Antibody Pair (726) (CAT#: APMAB-726LY)

Antibody Pairs

MCM4 Matched Antibody Pair (726) (CAT#: APMAB-726LY)

Related Products

Mouse Anti-MCM4 Recombinant Antibody (1A6) (CAT#: CBMAB-A5349-LY)

Mouse Anti-MCM4 Recombinant Antibody (CBFYM-0606) (CAT#: CBMAB-M0739-FY)

MCM4 Matched Antibody Pair (726) (CAT#: APMAB-726LY)

Rabbit Anti-MCM4 Recombinant Antibody (D3H6N) (CAT#: CBMAB-CP1477-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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