Mouse Anti-GPR22 Recombinant Antibody (EG1397) (V2LY-0226-LY865)

Name: Mouse Anti-GPR22 Recombinant Antibody (EG1397)
SKU: V2LY-0226-LY865
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

EG1397

Application

Immunogen

Synthetic peptide.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2b

Clonality

Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, BSA, glycerol

Preservative

Sodium azide

Concentration

1 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

G protein-coupled receptor 22

Entrez Gene ID

Human	2845
Mouse	73010

UniProt ID

Human	Q99680
Mouse	Q8BZL4

Function

Orphan G-protein coupled receptor. Seems to act through a G(i)/G(o) mediated pathway (PubMed:18539757).

May be involved in ciliogenesis (By similarity).

Biological Process

Cell projection organization Source: UniProtKB-KW
G protein-coupled receptor signaling pathway Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-45
Helical: 46-66
Cytoplasmic: 67-85
Helical: 86-106
Extracellular: 107-115
Helical: 116-136
Cytoplasmic: 137-156
Helical: 157-177
Extracellular: 178-208
Helical: 209-229
Cytoplasmic: 230-315
Helical: 316-336
Extracellular: 337-349
Helical: 350-370
Cytoplasmic: 371-433

Watkins, L. R., & Orlandi, C. (2021). In vitro profiling of orphan G protein coupled receptor (GPCR) constitutive activity. British Journal of Pharmacology, 178(15), 2963-2975.

Atanes, P., Ashik, T., & Persaud, S. J. (2021). Obesity-induced changes in human islet G protein-coupled receptor expression: Implications for metabolic regulation. Pharmacology & Therapeutics, 228, 107928.

Guns, L. A., Lories, R., & Cailotto, F. (2018). G-proteïne-gekoppelde-receptor 22 (GPR22): een nieuw doelwit in osteoartrose?.

Egerod, K. L., Petersen, N., Timshel, P. N., Rekling, J. C., Wang, Y., Liu, Q., ... & Gautron, L. (2018). Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms. Molecular metabolism, 12, 62-75.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-GPR22 Recombinant Antibody (CBFYH-0455) (CAT#: V2LY-0226-LY864)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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