Mouse Anti-GYG2 Recombinant Antibody (3D10) (V2LY-0226-LY2128)

Name: Mouse Anti-GYG2 Recombinant Antibody (3D10)
SKU: V2LY-0226-LY2128
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3D10

Application

WB, ELISA

Immunogen

GYG2 (aa 392-501) partial recombinant protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Glycogenin 2

Entrez Gene ID

8908

UniProt ID

O15488

Function

Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase.

Biological Process

Glycogen biosynthetic process Source: UniProtKB

Cellular Location

Cytosol; Cytoplasm

PTM

Self-glycosylated by the transfer of glucose residues from UDP-glucose to itself, forming an alpha-1,4-glycan of around 10 residues attached to Tyr-228.

De Filippi, P., Errichiello, E., Toscano, A., Mongini, T., Moggio, M., Ravaglia, S., ... & Danesino, C. (2023). Distribution of Exonic Variants in Glycogen Synthesis and Catabolism Genes in Late Onset Pompe Disease (LOPD). Current Issues in Molecular Biology, 45(4), 2847-2860.

Visuttijai, K., Hedberg-Oldfors, C., Thomsen, C., Glamuzina, E., Kornblum, C., Tasca, G., ... & Oldfors, A. (2020). Glycogenin is dispensable for glycogen synthesis in human muscle, and glycogenin deficiency causes polyglucosan storage. The Journal of Clinical Endocrinology & Metabolism, 105(2), 557-566.

Pursell, N., Gierut, J., Zhou, W., Dills, M., Diwanji, R., Gjorgjieva, M., ... & Lai, C. (2018). Inhibition of glycogen synthase II with RNAi prevents liver injury in mouse models of glycogen storage diseases. Molecular Therapy, 26(7), 1771-1782.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

GYG2 Matched Antibody Pair (521) (CAT#: APMAB-521LY)

GYG2 Matched Antibody Pair (522) (CAT#: APMAB-522LY)

Related Products

GYG2 Matched Antibody Pair (521) (CAT#: APMAB-521LY)

Mouse Anti-GYG2 Recombinant Antibody (CBLG1-2157) (CAT#: CBMAB-G5824-LY)

GYG2 Matched Antibody Pair (522) (CAT#: APMAB-522LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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