Mouse Recombinant OMD protein, His Tag (V2LY-0526-LY8728)

Name: Mouse Recombinant OMD protein, His Tag
SKU: V2LY-0526-LY8728
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Mouse

Tag

His Tag

Protein Construction

This product is Mouse Recombinant OMD protein, His Tag consist of Amino Acid: 1-423 and predicts a molecular mass of 48.8 kDa.

Molecule Mass

48.8 kDa

Sequence

Amino Acid: 1-423

Species

Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>96% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

osteomodulin

Function

May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the alpha(V)beta3-integrin (By similarity).

Biological Process

Cell adhesionIEA:UniProtKB-KW
Regulation of bone mineralizationIEA:InterPro

Cellular Location

Secreted, extracellular space, extracellular matrix

PTM

Binds keratan sulfate chains.

Zappia, J. (2023). Lack of osteomodulin is associated with skeletal development abnormalities and osteoarthritis.

Zappia, J., Tong, Q., Van der Cruyssen, R., Cornelis, F. M., Lambert, C., Pinto Coelho, T., ... & Henrotin, Y. (2023). Osteomodulin downregulation is associated with osteoarthritis development. Bone Research, 11(1), 49.

Tong, Q., Van der Cruyssen, R., Cornelis, F., Lambert, C., Coelho, T. P., Grisart, J., ... & Henrotin, Y. (2023). Osteomodulin down-regulation is associated with osteoarthritis development.

Li, Q., Chen, H., Liu, Y., & Bi, J. (2023). Osteomodulin contributes to keloid development by regulating p38 MAPK signaling. The Journal of Dermatology, 50(7), 895-905.

Skenteris, N. T., Seime, T., Witasp, A., Karlöf, E., Wasilewski, G. B., Heuschkel, M. A., ... & Matic, L. (2022). Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification. Clinical and Translational Medicine, 12(2), e682.

Gonçalves, I., Oduor, L., Matthes, F., Rakem, N., Meryn, J., Skenteris, N. T., ... & Bengtsson, E. (2022). Osteomodulin gene expression is associated with plaque calcification, stability, and fewer cardiovascular events in the CPIP Cohort. Stroke, 53(3), e79-e84.

Lin, W., Zhu, X., Gao, L., Mao, M., Gao, D., & Huang, Z. (2021). Osteomodulin positively regulates osteogenesis through interaction with BMP2. Cell Death & Disease, 12(2), 147.

Zappia, J., Van der Cruyssen, R., Sanchez, C., Lausberg, C., Lambert, C., Florin, A., ... & Henrotin, Y. (2021). Osteomodulin impacts positively the bone remodeling process in osteoarthritis. Osteoarthritis and Cartilage, 29, S111.

Skenteris, N. T., Seime, T., Witasp, A., Karlöf, E., Wasilewski, G., Chartou, M., ... & Matic, L. (2021). Osteomodulin is a novel gene in cardiovascular calcification. Atherosclerosis, 331, e93.

Lin, W., Gao, L., Jiang, W., Niu, C., Yuan, K., Hu, X., ... & Huang, Z. (2019). The role of osteomodulin on osteo/odontogenic differentiation in human dental pulp stem cells. BMC Oral Health, 19, 1-8.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant OMD protein, His Tag (CAT#: V2LY-0526-LY5886)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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