MUC20 Matched Antibody Pair (764) (APMAB-764LY)

Name: MUC20 Matched Antibody Pair (764)
SKU: APMAB-764LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-MUC20 polyclonal antibody, 100 ug

Detection Antibody

Anti-MUC20 Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The C-terminus of this family member associates with the multifunctional docking site of the MET proto-oncogene and suppresses activation of some downstream MET signaling cascades. The protein features a mucin tandem repeat domain that varies between two and six copies in most individuals. Multiple variants encoding different isoforms have been found for this gene. A related pseudogene, which is also located on chromosome 3, has been identified. [provided by RefSeq, Apr 2014]

Alternative Names

Mucin 20, Cell Surface Associated; MUC-20; Transmembrane Mucin MUC20S; Mucin-20; KIAA1359;

Entrez Gene ID

200958

UniProt ID

Q8N307

More Infomation

Xue, B., Guo, W. M., Jia, J. D., Kadeerhan, G., Liu, H. P., Bai, T., ... & Wang, D. W. (2022). MUC20 as a novel prognostic biomarker in ccRCC correlating with tumor immune microenvironment modulation. American journal of cancer research, 12(2), 695.

Fu, L., Yonemura, A., Yasuda-Yoshihara, N., Umemoto, T., Zhang, J., Yasuda, T., ... & Ishimoto, T. (2022). Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer. Gastric Cancer, 25(3), 542-557.

Wang, X., Shirazi, F., Yan, W., Liu, X., Wang, H., Orlowski, R. Z., & Wang, H. (2021). Mucin 20 modulates proteasome capacity through c‐Met signalling to increase carfilzomib sensitivity in mantle cell lymphoma. Journal of Cellular and Molecular Medicine, 25(21), 10164-10174.

Zheng, F., Yu, H., & Lu, J. (2019). High expression of MUC20 drives tumorigenesis and predicts poor survival in endometrial cancer. Journal of cellular biochemistry, 120(7), 11859-11866.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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